microbes and microbial metabolites. A mounting body of evidence indicates that the microbiome exerts significant effects on immune cells and CNS cells. These effects frequently result in the suppression or exacerbation of inflammatory responses, the latter of which can lead to severe tissue damage, ...
Does multiple myeloma cause amyloidosis? Why is multiple myeloma not a leukemia? Does multiple myeloma cause confusion? Is multiple myeloma a blood or bone cancer? What is the life expectancy of a multiple myeloma patient? Is stage 3 multiple myeloma terminal?
Discoid lupus is a more chronic, fixed expression of lupus of the skin that can lead to permanent scarring and skin color changes. Other internal diseases such as amyloidosis and sarcoidosis may cause skin symptoms and accompanying rashes. Lichen planus may appear as purple, itchy papules on ...
FMF is an autosomal recessive condition that primarily affects population of the Mediterranean basin. If undiagnosed effectively and treated with colchicine for life it may lead to serious consequences in terms of renal amyloidosis and renal failure. The gene (MEFV) responsible for this disease ...
Since the discovery of TMEM16A (anoctamin 1, ANO1) as Ca2+-activated Cl− channel, the protein was found to serve different physiological functions, d
Both upper and lower gastrointestinal symptoms were significant negative predictors of mBMI and the EQ-5D Index Score (p < 0.001 for all). Conclusions Gastrointestinal symptoms were common in patients with hereditary transthyretin amyloidosis and had a significant negative impact on their ...
prone to several health conditions, making health screening important at an early age. Hip dysplasia,disc disease, inherited autoimmune hypothyroidism, periodontal disease, renal amyloidosis, Chinese Beagle Syndrome (MLS), and Epilepsy are just a few of the common health conditions found with this ...
Thus, developing agents that target common structures of oligomers assembled from different amyloids could be a promising strategy to treat one amyloidosis or several amyloidoses. PD is the second most frequent neurodegenerative disease in humans, which is characterized pathologically by the formation of...
S.G. Browne - 《International Journal of Leprosy & Other Mycobacterial Diseases》 被引量: 17发表: 1965年 Some Less Common Pulmonary Diseases Alveolar HaemorrhagePulmonary Alveolar ProteinosisAmyloidosisTracheopathia and Bronchopathia OsteoplasticaAlveolar MicrolithiasisIdiopathic Pulmonary Hilar... A Seaton...
Finnish gelsolin amyloidosis (AGel amyloidosis) is an autosomal dominantly inherited systemic disorder with ophthalmologic, neurologic and dermatologic symptoms. Only the gelsolin (GSN) c.640G>A variant has been found in the Finnish patients thus far. The purpose of this study was to examine ...