This is a group of several inherited disorders that affect the shape and function of RBCs. People with it have abnormal hemoglobin protein, called hemoglobin S, in their RBCs. This can decrease oxygen levels. The RBCs of someone who has it take on a characteristic sickle shape. They burst e...
Common (1% to 10%): Decreased WBCs, decreased platelet counts Uncommon (0.1% to 1%): Decreased hemoglobin Frequency not reported: Abnormal hemoglobin, abnormal WBCs Postmarketing reports: Thrombocytopenia, aplastic anemia, leukocytoclastic vasculitis, thrombotic thrombocytopenic purpura/hemolytic uremic sy...
Common (1% to 10%): Dystonia, extrapyramidal symptoms (EPS), headache, other EPS-related events, parkinsonism Frequency not reported: Abnormal coordination, akinesia, bradykinesia, cerebrovascular adverse reactions, choreoathetosis, cognitive/motor impairment, dizziness, hypokinesia, increased mortality in ...
What are the physiologic implications of Sickle cell anemia? (What is abnormal about the physiology of people with this disease?) Describe the different types of blood transfusions. What are the normal ranges for each of the formed elements? WBC: RBC: Platelets: ...
Bacterial infection such as acute rhinopharyngitis is uncommon and usually presents with either persistent symptoms of an URTI lasting over a week or worsening course after initial improvement or acute onset with high fever and inflammatory changes confined to the pharynx. Fever is common in both ...
haematopoiesis preceded the acquisition of the Ph chromosome– In many ways, the function of the JAK2-V617F in Ph-negative at least in some patients – and implied that molecular abnormal- ities might precede the acquisition of BCR-ABL1.3,4 CMD resembles that of BCR-ABL1 in CML, but with...
For example, the pooled prevalence of dry eye disease (DED) was 16% in patients of SLE, and its symptoms as well as abnormal Schirmer's test were found in 26% and 24% of patients with SLE, respectively.4 Furthermore, the proportions of dry eye in other autoimmune diseases, such as ...
For example, the pooled prevalence of dry eye disease (DED) was 16% in patients of SLE, and its symptoms as well as abnormal Schirmer's test were found in 26% and 24% of patients with SLE, respectively.4 Furthermore, the proportions of dry eye in other autoimmune diseases, such as ...
Common (1% to 10%): Dystonia, extrapyramidal symptoms (EPS), headache, other EPS-related events, parkinsonism Frequency not reported: Abnormal coordination, akinesia, bradykinesia, cerebrovascular adverse reactions, choreoathetosis, cognitive/motor impairment, dizziness, hypokinesia, increased mortality in ...
events (up to 27%), increased INR (up to 27%), decreased leukocytes (up to 24.8%), prolonged activated partial thromboplastin time (up to 22%), decreased hemoglobin (up to 21.9%), increased prothrombin INR (up to 21%), febrile neutropenia (up to 15%), decreased WBC count (up to ...