Amyloidosis and Alzheimer's disease. Alzheimer's disease (AD) is the most frequent type of amyloidosis in humans and the commonest form of dementia. Extracellular A尾 amyloid deposits in the f... J Ghiso,B Frangione - 《Adv Drug Deliv Rev》 被引量: 256发表: 2002年 Macular Amyloidosis: ...
Therefore, it is imperative to type BM amyloidosis, preferably by LC-MS/MS, to ensure proper patient management. Furthermore, BM involvement by ATTR may be a marker for advanced stage of disease.doi:10.1093/ajcp/aqab191.200Dasari SChiu A...
Is multiple myeloma a hereditary disease? Is multiple myeloma cancer? Is multiple myeloma genetic? What is the difference between multiple myeloma and amyloidosis? How often does MGUS progress to multiple myeloma? What causes multiple myeloma?
Discoid lupus is a more chronic, fixed expression of lupus of the skin that can lead to permanent scarring and skin color changes. Other internal diseases such as amyloidosis and sarcoidosis may cause skin symptoms and accompanying rashes. Lichen planus may appear as purple, itchy papules on ...
We found that at the preclinical stage of the disease, the region-specific homeostatic identities were preserved. However, with the appearance of clinical signs, the region-specific signatures were partially lost and replaced with a neuroinflammation signature. While the same sets of genes were ...
Objectives: The presence of inflammation and neurofibrillary degeneration was evaluated in prion amyloidosis. Material and Methods: Cortical areas of variant Creutzfeldt-Jakob disease (CJD; n = 3), young sporadic CJD (n = 4), different Gerstmann-Sträussler-Scheinker’s disease patients (n = 5)...
146 Amyloidosis of Aβ42 as the common pathogenetic mechanism of all forms of Alzheimer\"s Disease DJ Selkoe 被引量: 0发表: 1996年 Hepatopancreatobiliary manifestations and complications associated with inflammatory bowel disease Diseases involving the hepatopancreatobiliary (HPB) system are frequently ...
Two main forms exist: hereditary and wild-type transthyretin amyloidosis, the former associated with transthyretin gene mutations. There are several disease manifestations; however, gastrointestinal complications are common in the hereditary form. The aim of this study was to explore the prevalence and ...
Thus, developing agents that target common structures of oligomers assembled from different amyloids could be a promising strategy to treat one amyloidosis or several amyloidoses. PD is the second most frequent neurodegenerative disease in humans, which is characterized pathologically by the formation of...
Amyloidosis Diphtheria and other severe respiratory infections Wegener's granulomatosis Thyroid cancer Lung cancer Lymphoma of the chest Between 1% and 2% of people who have intubation and mechanical ventilation will get tracheal stenosis. People who need prolonged ventilation are at the highest risk for...