Over time it is the weight of this experience that leads the patient to develop concomitant symptoms of chronic physical disability, anxiety, sleep disturbance, school absence, and social withdrawal.3 4 Parents report severe parenting stress and dysfunctional family roles. The malig...
Liver fat storage, also called hepatic steatosis, is increasingly common and represents a very frequent diagnosis in the medical field. Excess fat is not without consequences. In fact, hepatic steatosis contributes to the progression toward liver fibrosis. There are two main types of fatty liver di...
Just as financial privilege affords opportunities and stability, being raised in a mentally healthy family provides a foundation of emotional support, security, and guidance. In contrast, navigating the complexities of a dysfunctional family can feel like traversing a minefield, where every ste...
In human organisms, Smads function as signal transducers for the transforming growth factor β (TGF-β) family members (Hill1999). TGF-β family plays a crucial role in signal transduction, regulating biological processes such as gene expression, cell proliferation, differentiation, and apoptosis (Ma...
which predicts desirable life outcomes in many domains99. Furthermore, happiness has been related to reduced mind-wandering100, which is one of the critical roles of the DMN regions101. Correspondingly, unhappy people showed increased regional functional connectivity in the DMN102, whereas more succes...
Also, the rho-associated protein kinase (ROCK) pathway, FGF2-HRAS pathway, and RhoA-LIMK-Cofilin pathway were found to be enriched in our analysis that requires further investigation regarding their roles in actin dynamics and retinal remodeling. Also noteworthy, the Proteoglycans in cancer pathway...
1E). These results suggested that Ms6 plays important roles in both microsporogenesis and microgametogenesis in wheat. 3.2. Molecular cloning of the Ms6 gene We followed MutMap-based cloning approach to identify Ms6 gene [31]. Whole-genome resequencing of DNA bulked from 56 Ms6Ms6 (based on ...
discussions focused on novel roles of the choroid plexus in the development of hydrocephalus. During this session, topics introduced included the regulation and dysregulation of ion flux, the response of the choroid plexus to blood-breakdown products, evidence of CSF hypersecretion in the context of...
Diabetic vascular complications (DVCs), including macro- and micro- angiopathy, account for a high percentage of mortality in patients with diabetes mellitus (DM). Endothelial dysfunction is the initial and role step for the pathogenesis of DVCs. Hypergl
DMRTA2 has been found to regulate the expression of Hes1 gene, and this gene has been studied to have roles in cancer stem cell (CSC) maintenance, metastasis, and drug-induced apoptosis antagonism [67], [68]. The notable TF regulating the common genes between NFO and MO in TP was ...