The purpose of this chapter is to provide guidelines for the management of pediatric neuro-ophthalmic problems commonly seen in a general or pediatric ophthalmology practice. The most common neuro-ophthalmic entities encountered include functional visual loss, headaches, the "swollen" disc, and ...
Multiple sclerosis (MS) is the most common form of inflammatory disease in the CNS and is associated with autoimmune-mediated demyelination3,4. Other less frequent inflammatory diseases include Rasmussen’s encephalitis5and neuromyelitis optica (NMO)6. These diseases involve immune cell infiltrates in ...
Genome-wide association study of pediatric obsessive-compulsive traits: Shared genetic risk between traits and disorder Transl Psychiatry, 11 (2021), p. 91, 10.1038/s41398-020-01121-9 View in ScopusGoogle Scholar 141 Neumann A, Nolte IM, Pappa I, et al. A genome-wide association study of ...
Neuroimage. 2006;31(2):572–84. Article CAS PubMed Google Scholar Feng Y, Murphy MC, Hojo E, Li F, Roberts N. Magnetic resonance elastography in the study of neurodegenerative diseases. J Magn Reson Imaging. 2024;59(1):82–96. Article PubMed Google Scholar Wang Y, Wu Y, Luo L...
Common risk factors for psychiatric and other brain disorders are likely to converge on biological pathways influencing the development and maintenance of brain structure and function across life. Using structural MRI data from 45,615 individuals aged 3
Dear Editor,In the August 2009 issue of the Canadian Journal of Ophthalmology, John et al.revisited pediatric neurosar-coidosis. I recognize that the differential diagnosis of pediatric neurosarcoidosis is far from narrow, but a disease that is frequently missed when ocular sarcoidosis is considered...
Wagner KD, Ambrosini P, Rynn M, et al; Sertraline Pediatric Depression Study Group. Efficacy of sertraline in the treatment of children and adolescents with major depressive disorder: two randomized controlled trials. JAMA. 2003;290(8):1033-1041.ArticlePubMedGoogle ScholarCrossref 40. March J...
including pediatric brain tumors. Nevertheless, brain tumors remain the leading cause of mortality among all pediatric cancers [1]. Unlike in adult populations, pediatric brain tumors frequently arise in infratentorial regions [2], suggesting a spatiotemporal susceptibility to tumorigenesis. Indeed, trans...
Further, the twin-based heritability of a latent general psychopathology factor has been estimated at 43% in one study [31] and the SNP-heritability to 18%(SE = 0.10) [34] and 38%(SE = 0.16) [35] in two separate population-based pediatric samples. These findings suggest that ...
Epilepsy is a complex, chronic disorder that interacts with many aspects of human function. Psychological, social, and biological aspects of health have appropriately been the focus on many studies of persons with epilepsy. Results of clinical and basic investigati...