Concerning ECs repair, activation of transcription factors EGR1 and STAT3 is needed for transcribing sphingosine kinase 1 and sphingolipid transporter 2 to increase the generation and efflux of S1P [34, 35]. Then, the transition of S1PR1+ ECs amplifies and they activate endothelial regenerative ...
In total, 186,074 h of recordings were processed, of which 4796 h were verified to contain humpback whale vocalizations (for details on data processing see the methods section at the end of this manuscript). From the latter 3239 h contained exclusively humpback whale social calls and the rema...
This paper undertakes to explore the gerontological and social science literature for the purpose of highlighting that while ageing is a common phenomenon
that included reported recurrence, year of publication, timeframes of follow-up, type of study, and patient- and procedure-specific factors. We grouped therapeutic procedures for cumulative statistical analyses (Table1). Using this dataset, we assessed the efficacy of common surgical procedures employed...
in which numerous genes and environmental factors contribute to susceptibility in a manner still unclear. Several studies have failed to identify any association between genetic variants and common forms of migraine indicating that autosomal-dominant inheritance is unlikely, unless the penetrance of the ge...
The effects of individual functions combined with the rate of functioning governed by relationships between abiotic and biotic factors are key parameters to understand the way seafloor systems operate (Reiss et al., 2009). 3.5. Placing receptors at the centre of assessments A key criticism of EIA...
Cell Communication and Signaling (2023) 21:298 https://doi.org/10.1186/s12964-022-01016-w Cell Communication and Signaling REVIEW Open Access Common mechanisms underlying diabetic vascular complications: focus on the interaction of metabolic disorders, immuno‑inflammation, and endothelial ...
[41]. Further studies are necessary to clarify the aetiology of various CVID-associated phenotypes and confirm the epigenetic impact on immunodeficiencies. Detecting the environmental factors involved in epigenetic alterations could be useful to elaborate more specific diagnostic markers and more effective ...
Figure 2. Functional roles of lncRNAs. (A) As signal molecules, lncRNAs act either alone or in combination with proteins like transcription factors to mediate the transcription of downstream genes; (B) As decoys, lncRNAs either bind to functional proteins to block their activity or compete with ...
The induction of cell death in plants may depend on pathogen proteins called avirulence factors (Avrs). Virus-specific proteins occupy a special place among these. Viral effectors are variable, relatively small, and—in many cases—well-studied proteins that usually accumulate in plants to high ...