Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse. Fragile X syndrome (FXS) is a neurodevelopmental disorder caused by the loss-of-function of fragile X mental retardation protein (FMRP). The loss of FMRP f.....
Noun1.immunodeficiency- immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced immunological disorder- a disorder of the immune system acquired immune deficiency syndrome,AIDS- a serious (often fatal) disease of the immune ...
Common variable immunodeficiency (CVI) is a heterogenous disorder characterised by humoral immunodeficiency and recurrent bacterial pyogenic infections pri... C Carvalho,H Ferreira,R Costa,... 被引量: 0发表: 1997年 Cutaneous Granulomas in Common Variable Immunodeficiency: Case Report and Review of Lit...
Mental disorders such asdepression,anxiety, and somatic symptom disorder The cause of inflammatory bowel disease (IBD) is unknown, but it is thought to be the result of a defective immune system. In IBD, the immune system responds incorrectly to environmental triggers, which results in inflammatio...
twenty-five percent of people with cvid also have some type of autoimmune disorder , like immune thrombocytopenia (itp), hemolytic anemia (aiha), vitiligo, or multiple sclerosis. 3 people with cvid tend to have abnormally low levels of immunoglobulins, or infection-fighting antibodies, in their ...
Review: diagnosing common variable immunodeficiency disorder in the era of genome sequencing. Clin Rev Allergy Immunol. 2017; (in press)... R Ameratunga,K Lehnert,ST Woon,... - 《Clinical Reviews in Allergy & Immunology》 被引量: 11发表: 2017年 Review: Diagnosing Common Variable Immunodeficien...
Methylphenidate have a high potential for abuse and misuse, which can lead to the development of a substance use disorder, including addiction. Misuse and abuse of CNS stimulants, including methylphenidate, can result in overdose and death, and this risk is increased with higher doses or ...
In some people with this disorder, T cells also malfunction. Some people with immunodeficiency develop autoimmune disorders. In autoimmune disorders, the immune system attacks the body's own tissue. Examples are autoimmune blood disorders (such as immune thrombocytopenia, autoimmune hemolytic anemi...
Treatment of autoimmune disorders often requires a person to take medications that suppress their immune system. Psoriasis is an autoimmune disorder that often requires medications to suppress the immune system. Organ Transplants Immunosuppressant Medications ...
Also known as Lou Gehrig’s disease, ALS is an age-dependent rapidly progressive disorder of motor neurons with both sporadic and familial forms that is ultimately fatal. The disease is virtually always fatal and approximately 50% of patients die within 3–4 years after the onset of symptomatic...