We also created 3 new groupings: Structured Data, Relations, and Referential Semantics. In this breakdown of 7 groupings, we have ensured that the resulting semantic model distinguishes clearly between text semantics and referential semantics. This distinction is important for several reasons. The ...
Finally, deep semantic structure is necessary because it enables interoperability with all other types of medical information. With this CEM-based referential semantic model, structured data and NLP results can then be used together seamlessly in high-throughput phenotyping efforts. The effort in the ...
data and findings generated by the 100,000 Genomes Project, which is managed by Genomics England (a wholly owned company of the Department of Health and Social Care) and funded by the NIHR and NHS England with research infrastructure funding from the Wellcome Trust, Cancer Research UK and the...
The set of 20 “core” symptomatic adverse events (AEs) was reviewed and symptomatic AEs were selected if they had high potential to be meaningfully related to global changes in quality of life, physical condition, and/or emotional state (ie, the Global Impression of Change items that were ...
we carried out the largest genome-wide association study to date of DSM-IV-diagnosed AD. Genome-wide data on 14,904 individuals with AD and 37,944 controls from 28 case–control and family-based studies were meta-analyzed, stratified by genetic ancestry (European,n = 46,568; African,...
Oil on the skin makes for a breeding ground of bacteria, and bacteria will cause blemishes. Sleeping with not only your makeup on, but also the addition of oil, dirt and debris that has built up on the skin during the day, can absolutely trigger new blemishes. Here’s how to wash y...
The aim of this study was to evaluate the association of previously reported SNPs with prognosis using data from a hypothesis-generating pooled analysis of eight breast cancer survival GWAS from ten studies including 37,954 breast cancer cases [8]....
is Parsi, a cultural group that has resided in India for over 1000 years. Analysis of the data revealed that allele frequency differences between the different Indian language groups were small, and interestingly the variant alleles ofALOX5g.8322G>A and g.50778G>A, andPTPN22g.36677C>T ...
DNA samples that were negative by ASO-PCR were also amplified with N-ras gene-specific primers to confirm the integrity of the blood DNA sample (data not shown). Table 1. Detection of Clonal Circulating Cells in Plasma Cell Disorders by Cellular and Molecular Techniques DiseaseBone Marrow...
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide association study data, and tested for association in 34...