The code base to reproduce the statistical and replication analyses presented in this paper is available from a public source code repository (https://gitlab.oit.duke.edu/dcibioinformatics/pubs/calgb-80405-pqtl). The genotype and phenotype (clinical and protein) data for the CALGB/SWOG 80405 dis...
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so samples exceeding this cutoff were excluded. Alternatively, If a BAM file didnotmatch to the expected individual in the SNP genotype data, the sample was excluded except in 4 cases were the sample could be rescued by re-labeling it ...
Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina, USA R Rand Allingham, Pratap Challa, Yik Ying Teo & Michael A Hauser Intraocular Lens and Cataract Clinic, Aravind Eye Hospital, Madurai, India Aravind Haripriya, Rangappa Ramakrishnan, Kalpana Narendran & Rangaraj Ve...
We set the time horizon at 2030 and 2050, because 2050 is an estimated peak for infrastructure renewal (Walta, 2015) and because 2030 can aid in connecting the present to that long time-period. We collected the quantitative data in multiple face-to-face seminars – instead of the common ...
This implies that the Center Test, especially its reading section, was measuring general English proficiency rather than reading abilities alone, which skewed the whole data set to close on the unitary model. If so, since the pronunciation and grammar sections in the Center Test were excluded at...
STATA SE12.0 (STATAcorp LP, College station, TX) was used to analyze and generate summary statistics of the data set. We compared variation frequency between cases and controls using either the Chi Square test (χ2) or Fisher's exact test and used the Mann–Whitney ...
clinical psychiatrist and Duke University professor Robin Gurwitch, even though they may deal with the fear and stressors Crawford outlined. It's something high school senior Jordyne Lewis has experienced since she and her classmates were placed in soft lockdown for five ...
Using stratified LD score regression (s-LDSC) with single-nucleus RNA-sequencing (snRNA-seq) data from adult human myocardial samples22, we observed enriched GWAS heritability near cardiomyocyte-specific genes for DCD, which may be explained by the inclusion of nonspecific intraventricular conduction ...
We report a multi-ancestry genome-wide association study on liver cirrhosis and its associated endophenotypes, alanine aminotransferase (ALT) and γ-glutamyl transferase. Using data from 12 cohorts, including 18,265 cases with cirrhosis, 1,782,047 contro