Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a lifetime risk of one in 350 people and an unmet need for disease-modifying therapies. We conducted a cross-ancestry genome-wide association study (GWAS) including 29,612 patients with ALS and 122,656 controls, which...
Lichen sclerosus is another condition that can cause anal irritation. This relatively rare condition causes white, wrinkled skin changes and scarring in the genital region, including the perianal region. People with female genitalia are more likely to be affected.5 ...
The laboratory mouse is the most used species of animals in research, with an estimate of 61% of laboratory animals used in the European Union in 2017 [12]. Therefore, A&A in mice may constitute a major part of the problem with laboratory animal anesthesia. There are at least three inval...
Our results suggest that the physiological and metabolic processes influenced by risk-associated changes in the gut microbiome vary across diseases. For CAD and T2D, the gut microbiome score exhibited predictive performance comparable to SBP, cholesterol levels and triglycerides. For CAD, AD and prostat...
"In some cases, lifestyle changes such as weight loss may be enough, while medical surgical intervention may be required in others." In rare cases, orthodontic devices may be needed to adjust the position of the child's jaw. However, if the child's sleep apnea is caused by...
Headhunter20UncategorizedComments Offon Joy riding around in this time machine The entire barrage of climate articles one cannot easily avoid seeing are full of garbage. Yes, it is summer, and because of massive changes in the jet stream certain places are exceptionally hot, but that is nothing...
Disclaimer: The payment schedule below is based on my personal analysis of information from the OMA as of December 6, 2024. It would not surprise me if there were more changes. Do NOT use this as your sole source of planning. Contact info@oma.org with any questions. On Nov. 1, 2024,...
testosterone can contribute to a range of physical and emotional symptoms, including depression, that can affect both men and women. Low testosterone levels in men can lead to changes in mood and mental function, as testosterone has an impact on various physical and cognitive processes in the ...
Serum metabolome and lipidome changes in adult patients with primary dengue infection. PLOS Negl. Trop. Dis. 7, e2373 (2013). PubMed PubMed Central Google Scholar Greco, F. A. et al. The Janus-faced nature of IDO1 in infectious diseases: challenges and therapeutic opportunities. Future ...
Conclusion: Common genetic variants related to impaired kidney function in adults already lead to subclinical changes in childhood kidney outcomes. The well-known associations of kidney measures in early life with kidney disease in later life may at least be partly explained by common genetic variants...