Importantly, they also help explain why attempts to find new chemo drugs based solely on stopping mitosis have been so disappointing, Weaver says. “We’ve been barking up the wrong tree,” she says. “We need to refocus our efforts on screwing up mitosis — on making chromosomal se...
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SAN ANTONIO, Texas — Premenopausal women with Luminal A breast cancer, a common, intrinsic subtype, can consider skipping chemotherapy altogether and still expect a good prognosis, even when they are node positive, according to a new analysis of an old Danish study. ...
Chemotherapy.Like radiation therapy, certain chemotherapy drugs can also raise risk for a secondary cancer. Chemotherapy for ovarian cancer typically includes a platinum-based drug, such as cisplatin or carboplatin. Your treatment could also include another type of chemotherapy called an alkylating agent,...
Bevacizumab (Avastin(R)) Added To Common Chemotherapies Significantly Increases Tumour Shrinkage In HER2-negative Breast CancerRoche
And that is what their collaborators at the University of Tokyo and the University of Cyprus found when they tested the drug on breast cancer in animal models. The timing and dosage of the dexamethasone treatment needs more testing to show how it would be most effective in humans, the researc...
Tong AW, Lee J, Wang RM, Dalton WS, Tsuruo T, Fay JW, Stone MJ: Elimination of chemoresistant multiple myeloma clonogenic colony-forming cells by combined treatment with a plasma cell-reactive monoclonal antibody and a P-glycoprotein-reactive monoclonal antibody. Cancer Res. 1989, 49 (17):...
Cutaneous side effects of anti-cancer agents affecting the skin, hair, nails and mucosa are commonly seen in the in-patient and out-patient settings. Here, we will review the various common cutaneous side effects by chemotherapy type: cytotoxic chemotherapies, EGFR inhibitors , multitargeted small...
cancer cells with chemoresistance. A recent research revealed the modulation of RGS2 expression by DNA methylation and histone deacetylation particularly in the chemoresistant ovarian cancer cells, and as a result, the expression of RGS2 is declined in the ovarian cancer cells resistant to drugs [...
Doxorubicin is an anthracycline chemotherapy drug that is often used with other types of chemotherapies to treat bladder andbreast cancer, leukemia, and lymphoma, among othertypes of cancer. Although it is an anti-cancer drug, it has been found to potentially cause serious heart issues and...