Both blood vessels and nerves are vital channels to and from tissues. Recent genetic insights show that they have much more in common than was originally anticipated. They use similar signals and principles to differentiate, grow and navigate towards their targets. Moreover, the vascular and nervou...
Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-transcriptional gene silencing through base-pair binding on their target mRNAs. We identified nonlinear changes in age-related microRNAs by analyzing whole blood from
Goat diseases are economically significant and potential to achieve many national and international assurances on food security, poverty alleviation and improved nutritional standard. These diseases pose several constraints to the development
Today, blood tests can do many things, because doctors and scientists have identified many substances in the blood that can tell you if you have an infection, an autoimmune disease, a marker for cancer, inherited diseases, and even blood clots or heart failure. Blood tests are also used to...
(Supplementary Fig.8). However, since PolyMR was not designed for binary outcomes, we selected six quantitative biomarkers (total cholesterol, blood glucose, HbA1c, HDL, LDL, triglycerides, and urate) as outcomes to assess the potential non-linear causal effects of coffee intake and tea intake...
Then, by analyzing a blood sample for simple sugars, the doctor determines the patient's ability to digest the lactose and absorb the simple sugars. A lower-than-normal value usually means a lactase deficiency. Are gluten-sensitive enteropathy, other gastrointestinal diseases, or psychological factor...
(called GSMR) that performs a multi-SNP Mendelian randomization analysis using summary-level data from genome-wide association studies to test the causal associations of BMI, waist-to-hip ratio, serum cholesterols, blood pressures, height, and years of schooling (EduYears) with common diseases (...
list of common medical abbreviations, acronyms, and terminology used by doctors and other health- care professionals. You can use this list of medical abbreviations and acronyms written by our doctors the next time you can't understand what is on your prescription package, blood test results, or...
Preimplantation genetic testing (PGT) of in-vitro-fertilized embryos has been proposed as a method to reduce transmission of common disease; however, more comprehensive embryo genetic assessment, combining the effects of common variants and rare variants
et al. An atlas of genetic correlations across human diseases and traits. Nat. Genet. 47, 1236–1241 (2015). CAS PubMed PubMed Central Google Scholar Okbay, A. et al. Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide...