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In our work, genomic SNP markers were used to analyze the breeding signatures of GCA as revealed by the genetic variation in a recurrent selection population. The objectives of our study were (1) to estimate genetic diversity of genome-wide SNPs in different groups of the rapeseed restorer ...
DNA damaging agents are mutagenic, as demonstrated by the increased risk of secondary cancers following treatment with radiotherapy or chemotherapeutics such as etoposide, and also by the mutational signatures associated with some treatments (Alexandrov et al, 2013; Murugaesu et al, 2015). Inhibition ...
Bioinformatic validation and machine learning-based exploration of purine metabolism-related gene signatures in the context of immunotherapeutic strategies for nonspecific orbital inflammation. Front. Immunol. 15 (2024). 16. Subramanian, A. et al. Gene set enrichment analysis: A knowledge-based approach...
Importantly, the paradigm of multitarget or smart hybrids [112] having two pharmacophoric molecular signatures is purported to be one of the promising strategies targeting cancer. Intriguingly, since cancer growth is fueled by a plethora of signaling gymnastics, HDAC inhibitors with dual effects are...
Together, this combined experimental approach enables us to understand the alloying mechanism of Rh with Cu and yields important signatures of the atomic sites that are useful in benchmarking vibrational data.doi:10.1002/cctc.201901488John Wiley & Sons, LtdChemCatChem...
To test the score’s potential to predict future severe outcomes, the sub-group of patients who met a severe outcome for the first time after the day of blood draw (n = 29) was identified. The time from blood draw to first outcome was 1–13 days with a median of 4 days and the ...
Despite research on the Intrusion Detection field has been active since 1980s, a num- ber of questions about their effectiveness still remain unanswered [2]. This is mainly due to the difficulties in constructing both attack signatures and normal behaviour effective models. The misuse-based ...
Gene expression-based prognostic signatures in lung cancer: ready for clinical use? J Natl Cancer Inst 2010;102:464–474. 38 Bryant CM, Albertus DL, Kim S, et al. Clinically relevant characterization of lung adenocarcinoma subtypes based on cellular pathways: an international validation study. ...
iterates over a plurality of measurement epochs; and for a respective measurement epoch of the plurality of measurement epochs: if a respective monitoring sensor measurement of the one or more monitoring sensor measurements indicates a first device context that is physically incompatible with a second...