Durvalumab for recurrent or metastatic head and neck squamous cell carcinoma: results from a single-arm, phase II study in patients with ≥25% tumour cell PD-L1 expression who have progressed on platinum-based chemotherapy Eur J Cancer, 107 (2019), pp. 142-152 View PDFView articleView in ...
While this was successful in stealthing a retargeted version of H, it was not effective for the endogenous form indicating shared epitopes for viral entry and antibody neutralization warranting the need for further insight on the matter [81]. Another approach for stealthing oncolytic MeV from ...
the novelty of its use limits its radiomics data correlation with long-term outcomes such as metastatic recurrence or time to castration resistance. Moreover, despite
In the present work, we first used WGCNA to analyse ESCA mRNA datasets from The Cancer Genome Atlas (TCGA) to predict significant gene modules. Second, gene modules were combined with predicted targets of key CKI components to form a drug-gene-disease network and further analysed. In addition,...
Future research, in the form of high-quality controlled trials, is warranted to investigate whether the combination of formal and informal care is of additional value for patients with cancer in terms of information needs and supportive care compared to solely receiving care as usual. As shown in...
no long-term results available yet *Multiple harvests, STSG = split thickness skin graft; CEA = Cultured Epithelial Autograft; CDEA = Cultured Dermo-Epidermal Autograft; dS = denovoSkin. Take rates for STSG were 80–100% in all areas except the gluteal and perineal regions, where they ranged...
Figure 1. Examples for mis-registration in different regions of whole-body PET/CT scans: (A) Neck muscle relaxation leading to misalignment of the head, (B) patient respiration leading to artifacts in the upper diaphragm, (C) peristaltic motion and respiration leading to misalignment of liver ...
Over the last several decades, tremendous progress in the optimization of therapies for various medical conditions, such as cancer, has been realized. Many factors underlie this therapeutic success, including optimization of clinical trial design, new pathway-specific pharmaceuticals and the coordination ...
A 59-year-old gentleman, native of and living in Pune, presented at our hospital in Kollam, Kerala, India seeking Ayurvedic treatment for his complaints. 2.2. Main concerns and symptoms of the patient He presented with symptoms of stiffness, swelling and pain in neck, back and bilateral hip...
The first prospective clinical trials showed promising local disease control, especially with a short-term perspective [3]. The immunological impact of focal therapies, as well as the immunotherapy of PC itself, have been addressed by academic research for years. Thus, it was a substantial break...