The molecular basis for the natural tumor selectivity of MeV is primarily based on its receptor usage and its sensitivity towards the anti-viral interferon (IFN) response, which is often compromised in cancer cells. It should be noted that most of the pre-clinical and clinical constructs ...
High-speed tomography and radiography were also used to image commercial 18650 cells during thermal runaway2. Here, we present a combined synchrotron X-ray tomographic microscopy (SRXTM) and scanning X-ray diffraction (SXRD) experiment. By combining SRXTM and SXRD, we show that it is possible...
Increasing evidence shows that cells develop intracellular protein-rich organelles that grow and fuse, allowing certain molecules to become locally enriched while excluding others1. Intracellular liquid–liquid phase separation (LLPS) processes seem to be a common route to achieving spatial organization of...
Serine-threonine kinase11 (STK11) is a tumor suppressor gene which plays a key role in regulating cell growth and apoptosis. It is widely known as a multitasking kinase and engaged in cell polarity, cell cycle arrest, chromatin remodeling, energy metabolism, and Wnt signaling. The substitutions ...
View PDFView articleView in ScopusGoogle Scholar [5] N.E. O’Conner, J.B. Mulliken, S. Banks-Schlegel, O. Kehinde, H. Green Grafting of burns with cultured epithelium prepared from autologous epidermal cells Lancet, 1 (8211) (1981), pp. 75-78, 10.1016/S0140-6736(81)90006-4 Google...
Assessment of signalling events in antigen-specific T-cells by combining phosphoepitope specific flow cytometry and MHC-multimer stainingR. ThieleM. KappE. BaumeisterK. FickG. StuhlerA. OpitzH. EinseleG. Grigoleit
In this study, we developed a new bioreactor chamber for cardiac TE that allows providing the cells with a combination of bidirectional perfusion and electrical stimulation and monitoring the construct functionality without interrupting the culture. The effects of the electrical stimulation in static condi...
the intermediates formed often contain carbonyl group (e.g., in form of aldehyde) which are very reactive under physiological conditions and cannot accumulate to a high level due to toxicity to cells. To our knowledge, synthetic biological routes proposed for diol production almost exclusively use ...
Fig. 4: Sensitivity of palbociclib-resistant cells to the combination of capivasertib and fulvestrant. Full size image Anti-tumour efficacy of the capivasertib and fulvestrant combination in palbociclib insensitive PDX models Fig. 5: In vivo anti-tumour activity of the combination of capivasertib ...
In this paper, we report an in vitro co-culture system that combines mammalian cells and algae, Chlorococcum littorale, to create a three-dimensional (3-D) tissue. While the C2C12 mouse myoblasts and rat cardiac cells consumed oxygen actively, intense ox