Furthermore, the performance of the mixture of these four strains was clearly improved, reaching the maximal removal efficiency of 64.1% also at the optimal temperature of 35 °C, which was 8.7% higher than that of the best individual stain. This improved was largely attributed to the mixed...
The therapeutic efficacy of tLNP/siHBV was evaluated in mouse models of HBV replication. Higher than 2log10IU/mL decrease of viral antigen (2.65log10reduction of HBsAg, 1.82log10reduction of HBeAg) and HBV DNA (2.29log10reduction) were observed after a single dose of tLNP/siHBV at the dos...
Science China Life Sciences(2024) Nature Communications (Nat Commun)ISSN2041-1723(online) Sign up for theNature Briefing: Translational Researchnewsletter — top stories in biotechnology, drug discovery and pharma. Email address Sign up I agree my information will be processed in accordance with the...
Thin sections were examined with a Philips 300 electron microscope (Department of Biology, National and Kapodistrian University of Athens) and a JEOL 100S TEM (Faculty of Crop Science of the Agricultural University of Athens (AUA)). Studied samples (3 plants/treatment) were obtained after 24 h...
We are grateful for the support by the high level talents (333 Project) of Jiangsu Province (Grant No. BRA2019024); the National Natural Science Foundation of China (81602728, 81571789, 81771980); the Key project Foundation of Jiangsu health and Health Committee (Grant No. H2018114); the So...
Expression of higher eukaryotic genes as soluble, stable recombinant proteins is still a bottleneck step in biochemical and structural studies of novel proteins today. Correct identification of stable domains/fragments within the open reading frame (ORF), combined with proper cloning strategies, can grea...
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(2) the period of industrial production (1882–1889), when several British factories were established on Japanese soil, leading to faster yet traditional manufacture, as well as a change in the wallpaper design; and (3) the mass-produced commodity period (1890–1905), where the patterns were...