CPS 是 Combined Positive Score 的缩写,中文可以翻译为“综合阳性评分”。这是一种用于评估肿瘤样本中 PD-L1 表达水平的评分系统。PD-L1 (程序性死亡配体1) 是一种在某些类型的癌细胞上表达的蛋白质,它可以通过与免疫细胞上的 PD-1 受体结合来帮助肿瘤逃避人体免疫系统的攻击。 在不同的癌症类型和不同的研究...
Concordance of PD-L1 combined positive score (CPS) analysis between primary gastric cancer and matched peritoneal metastasis.doi:10.1200/JCO.2024.42.16_suppl.e1606816e16068#Background:Peritoneum represents one of the most common metastatic sites of gastroesophageal adenocarcinoma (GEA) and is associated...
[C] + cetuximab) improved overall survival (OS) in PD-L1 combined positive score (CPS) ≥20 and CPS ≥1 populations and led to noninferior OS in the total population with favorable safety; first-line P+C vs E had superior OS in CPS ≥20, CPS ≥1, and total populations with ...
Before PSM, in the RCIT group, 27 patients (35.5%) had available PD-L1 expression, of which 3 were negative expression of PD-L1 (combined positive score (CPS) < 1) and 24 were positive (CPS ≥ 1). In the CIT group, 23 patients (35.9%) had available PD-L1 expression, of...
[C] + cetuximab) improved overall survival (OS) in PD-L1 combined positive score (CPS) ≥20 and CPS ≥1 populations and led to noninferior OS in the total population with favorable safety; first-line P+C vs E had superior OS in CPS ≥20, CPS ≥1, and total populations with ...
PD-L1 expression was reported as a combined positive score (CPS), defined as the number of PD-L1-positive cells (tumor cells, lymphocytes, and macrophages) divided by the total number of viable tumor cells and multiplied by 100. Statistical analysis Based on a two-sided type 1 error of ...
We explored the associations of MPR with PD-L1 expression and microsatellite instability (MSI) status. In the combined positive score (CPS) < 1% subgroup (n = 45), the MPR rates were 27.3% and 17.4% in the CA-SAP and SAP groups, respectively (P = 0.331). Among the 54...
Tumor tissue for determination of PD-L1 status with combined positive score (CPS) must be provided from ≤ 6 months before study treatment. Antitumor activity was assessed by RECIST v1.1. Results: As of Sep 9, 2020, 34 pts (73.5% male, median age 63.1 yrs [29-75], 76.5% G and 23.5...
Patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative BC at high risk of relapse [defined as no pathological complete response after neoadjuvant chemotherapy and a clinical, pathological stage, estrogen receptor, grading (CPS-EG) score ≥3 or 2/ypN+] were random...
Carnitine plays a positive role in human health and function. It promotes the conversion and oxidation of fatty acids, aiding in the conversion of fat into energy (Del Vecchio et al., 2017). Additionally, it regulates blood pressure and blood glucose balance, reducing the risk of chronic ...