Patel, D. Bocangel, S. Chada, and R. Ramesh, "Vitamin E succinate in combination with mda-7 results in enhanced human ovarian tumor cell killing through modulation of extrinsic and intrinsic apoptotic pathways," Cancer Letters, vol. 254, no. 2, pp. 217-226, 2007....
Breast cancer is considered a very complex and dangerous disease with multiple questions [1]. Its increasing global incidence emphasizes the need to explore novel, effective, and safe anti-cancer therapy [2]. Concerning breast cancer treatment, surgical removal of the tumor was found to be curativ...
1. Exclusion criteria comprised the following: (1) dietary energy intake below 800 or over 4200 kcal/day for male and below 500 or more than 3500 kcal/day for female [29]; (2) participants with missing triglyceride-glucose index and its combinations with indicators of obesity; (3) ...
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Bromelain and N-acetylcysteine are two natural, sulfhydryl-containing compounds with good safety profiles which have been investigated for their benefits and application in health and disease for more than fifty years. As such, the potential values of th
This combination treatment completely inhibited phosphorylation of the HER family members (HER1, 2, 3), binding of PI3K regulatory unit p85 to HER3 and downstream Akt activity even after androgen depletion. Furthermore, in a LNCaP mouse xenograft model, the MP470-Erlotinib combination produced 30...
wherein in the case of increased stress the body's own immune activity, the numbers of NK cells and leukocytes are increased. 8. The pharmaceutical composition for use according to any of claims 1 to 7, wherein the active substance combination contains 20 - 200 mg 1-(2-diethylaminoethyl...
Infliximab promotes anti-inflammatory effects mainly by inhibiting TNF-α in colonic macrophages and suppressing a pro-inflammatory cascade, thereby relieving structural damage to the mucosa5. (2) Blockade of T cell homing to sites of inflammation. Upon activation, T cells express integrin α4β7 ...
This presentation will provide an overview of the differences and similarities of E&L requirements between pharmaceutical products and medical devices. The key elements regarding E&L testing design of combination products will be discussed. Several case
The method involves selecting a test signal-combination from a given set of test signal-combinations. The selected test signal-combination is created at neurons, and an output signal of another neuron is detected. A partial-test signal for the selected test signal-combination is stored, when the...