The response spectrum method is used to compute inertial response, estimates of response quantities developed for each mode, each direction of excitation and each input, if multiple inputs are considered. The total response is then formed by summing over all modal component, spatial component and e...
response spectrum analysisThis paper deals with the construction of seismic response interaction diagrams that show the correlation of multiple responses and are important to determine the critical combination of modal responses. Many design problems, such as column design under combined axial force and ...
A new response-spectrum mode superposition method, entirely in real value form, is developed to analyze the maximum structural response under earthquake ground motion for generally damped linear systems with repeated eigenvalues and defective eigenvectors. This algorithm has clear physical concepts and is...
The IUPUI_CCBB method utilized gene expression data as its only data source, and computed a Pearson correlation between gene expression profiles of compound pairs using genes that were differentially expressed in at least one compound treatment13. The IUPUI_CCBB method is predicated on the hypothesis...
Alzheimer’s Disease (AD) significantly aggravates human dignity and quality of life. While newly approved amyloid immunotherapy has been reported, effective AD drugs remain to be identified. Here, we propose a novel AI-driven drug-repurposing method, DeepDrug, to identify a lead combination of ap...
No statistical method was used to predetermine sample sizes, but our sample sizes are similar to those reported in previous publications20,56. Data distribution was assumed to be normal, but this was not formally tested. No data were excluded from the analysis. To compare growth curves, we ...
A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation Ann Intern Med, 130 (1999), pp. 461-470 CrossrefView in ScopusGoogle Scholar 16 A.E. Berden, F. Ferrario, E.C. Hagen, et al. Histopathologic classification of ANCA-associated ...
Although this method is recommended by the Cochrane Collaboration and the robustness of the results was validated with a sensitivity analysis, the findings should be interpreted with caution. Moreover, given the scarcity of available data, we could not perform a subgroup analysis by severity of ED...
In addition, an oxa-Pictet-Spengler reaction was used as a spirocycle-generating method to combine the indole-derived fragment 4H-pyrano-indole and a griseofulvin derivative (GF-THPI)29. The spirocyclic installation of chromanone fragments to ketone-containing NP derivatives was achieved via the ...
While we could detect chromatographic peaks attributable to B in serum samples, the sensitivity of our method did not always reliably allow its quantification. Clinical PK data suggests that B serum levels during continuous treatment of Parkinson’s disease can be relatively low; i.e., <5 ng...