Hypertensive patients (clinic blood pressure [ BP] >= 140/90 mmHg) received telmisartan 40 or 80 mg either alone or in combination with HCTZ 12.5 mg for 8 weeks. Treatment could be adjusted if clinic BP remained >= 140/90 mmHg. Clinic BP was measured in the morning prior to medication,...
efficacy and safety of the combination of AML þ Patients were instructed and reinforced to take their OM with and without hydrochlorothiazide (HCTZ) medication at the same time each day, preferably in in a 44-week open-label extension (OLE) of the the morning, though treatment accountability...
(0.2) Prior anti-hypertensive medication (most common) Hydrochlorothiazide 3160 (47.5) Amlodipine 2663 (40.0) Ramipril 1484 (22.3) Bisoprolol 928 (13.9) Metoprolol 801 (12.0) Torasemide 696 (10.5) 66.0 170.0 84.0 28.7 160.0 90.0 7.8 SD, standard deviation; kg, kilogram; m2, square-meter; ...
The author concluded that further studies and combination in one pill would be appealing with respect to the efficient prevention of cardiovascular end points and would potentially increase treatment adherence in patients who have been prescribed long term poly-medication therapy. Investigations carried by...
Treatments of combined with medication of netrilix and enapril on heart failure induced by hypertensive heart disease; 钠催离及依那普利联用治疗高血压性心脏病心力衰竭 2. The effect of Enapril on glomerular extracellular matrix accumulation in rats with 5/6 renal mass ablation; 依那普利对大鼠...
The first study is a multiclinic, randomized, double-blind trial in 475 hypertensive patients from the Veterans Administration Cooperative Study Group,9 comparing an angiotensin-converting enzyme (ACE) inhibitor (captopril), first as monotherapy and then in combination with h...
To obtain blood pressure (BP) target goals most patients require treatment with more than one hypertension medication. However, the potential differing effects on BP regulation of combination therapy depending on the time-of-day of administration have scarcely been investigated. Accordingly, the authors...
OM+AML+HCTZ was initiated in a subset of patients from each of the 3 dual-combination groups at wk 4 and continued until wk 12.The primary safety cohort (n=2302) for the assessment of AEs was defined as patients who took at least 1 dose of study medication at or beyond wk 4....
Tolerability of study medication was comparable between all three groups. In conclusion, switching to V/HCTZ combination therapy provides an additional lowering of BP compared to dosage increase of the thiazide in patients with BP insufficiently controlled by HCTZ 12.5 mg monotherapy....
and PDC, adjusted for age, gender, business segment, RxRisk disease categories, average co-pay and concurrent cardiovascular-related medication utilization./p pResults/p pThe study cohort consisted of 48,212 patients; 72.5% used HCTZ, 13.2% ACEI/HCTZ, 9.3% ARB/HCTZ, and 5.0% BB/HCTZ. Mean...