Microsatellite unstable colo- rectal cancer cell lines with truncating TGFbRII mutations remain sensitive to endogenous TGFb. J Pathol 2007; 213:257-265.Baker K,Raut P,Jass JR.Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGF...
1)Colorectal cancer cell大肠癌细胞 1.Effects of fibroblasts-colorectal cancer cells interaction on EMMPRIN expression in colorectal cancer cells;成纤维细胞与大肠癌细胞相互作用对大肠癌细胞表达EMMPRIN的影响 2.Two human colorectal cancer cell lines with different degrees of radiosensitivity,LOVO and SW480,...
Microsatellite unstable colorectal cancer cell lines with truncating TGFbRII mutations remain sensitive to endoge- nous TGFb. J Pathol 2007;213:257-65.Baker K,Raut P,Jass JR.Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGFbeta...
Colorectal Cancer Cell Lines Lack the Molecular Heterogeneity of Clinical Colorectal Tumors Clin. Colorectal Cancer, 9, 40-47.Auman JT, McLeod HL: Colorectal cancer cell lines lack the molecular heterogeneity of clinical colorectal tumors. Clin ... James,Todd,Auman,... - 《Clinical Colorectal ...
These data indicated that P6C cells share similar proliferation properties with differentiated colorectal cancer cell lines when grown attached to cell culture dishes. Xenograft tumor from a single cell-derived holoclone We next addressed whether a single P6C cell could result in a xenograft tumor, ...
Bioinformatics datasets and academic articles were used in the initial step to screen certain prospective colorectal cancer drugs. The anti-tumor potential of a few drugs was then examined in the colorectal cancer cell lines HCT-116 and HT-29 to validate their effectiveness against colorectal cancer...
When functional annotations of related DEGs were analyzed, there were increased numbers of disease functions attributed to co-culturing with viableF.nucleatumcompared to HKF.nucleatum23726 (Supplementary Fig.4). Whereas the predicted activation state of “apoptosis in colorectal cancer cell lines” was ...
et al. The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets. Nat. Commun. 6, 7002 (2015). CAS PubMed Google Scholar Cremolini, C. et al. Negative hyper-selection of metastatic colorectal cancer patients for anti-EGFR monoclonal antibodies: the ...
However, the number of publications characterizing cancer cell lines at a molecular level is far behind the number of articles using cancer cell lines as model systems (18), and only few studies have been conducted on whether in vitro cultured cell lines can serve as suitable models for human...
Previous work from our group using isogenic colorectal cancer cell lines has demonstrated that EV cargo content is regulated in a KRAS dependent manner, including proteins, miRNAs, circular RNAs, mRNAs, and long coding and non-coding RNAs (lncRNAs)9,10,11,12. We also showed that EVs can medi...