To characterize the spatial variation of the mucosa-associated adherent mycobiota along the large intestine in individuals with a normal-colon, we performed eukaryotic rRNA operon's internal transcribed spacer-2 sequencing to profile fungal community composition and structure in 70 mucosal biopsies taken...
Generally, luminal SLCFAs are derived from either lipolysis of dietary fats or host/bacterial fatty acid synthesis [43,51,52]. A previous study reports normal expression of enzymes for host lipolysis, transport and lipogenesis at the mRNA level in NMS model rats [31]. Moreover, SLCFAs with ...
qPCR validation of DEGs in the colonic mucosa of HES goats compared with the LES goats (the difference was identified by independent sample T-test). The values are presented as log2 (fold change). F Effects of enteral starch on the gene expression which involved in colonic mucosal T helper...
Normal colonic mucosa in hereditary non-polyposis colorectal cancer shows no generalized increase in somatic mutations. Br J Cancer 1995; 71: 1077-80.Williams GT, Geraghty JM, Campbell F, Appleton MAC, Williams ED. Normal colonic mucosa in hereditary non-polyposis colorectal cancer shows no ...
model rats with oral gavage of PBS presented greater stool pellet output within 60 min. Enhanced defecation number was effectively attenuated and ultimately returned to normal after 14 days of neomycin treatment. The gut transit time became prolonged in neomycin-treated NMS rats, but was shorter tha...
B. et al. Effects of supplemental calcium and vitamin D on tight-junction proteins and mucin-12 expression in the normal rectal mucosa of colorectal adenoma patients. Mol. Carcinog. 1–12 (2019) https://doi.org/10.1002/mc.23010. Zemel, M. B. & Sun, X. Dietary calcium and dairy ...
Altered gene expression in normal colonic mucosa of individuals with polyps of the colon. Diseases of the Colon and Rectum . 2005; 48 (12):2329–2335.Hao CY, Moore DH, Chiu YS, et al. Altered gene expression in normal colonic mucosa of individuals with polyps of the colon. Dis Colon ...
normal mouse colonic mucosa. Peptide biodistribution was consistent with rapid renal clearance. No signs of acute toxicity were found on either animal necropsy or serum hematology and chemistries. Human colonoids provide a clinically relevant preclinical model to evaluate the specific uptake of a NIR ...
41-9). The same phenomenon is evident in dorsal column nuclei where firing of second-order neurons to colorectal distension becomes sensitized after inflammation of the colon produced by application of mustard oil to the mucosa (97). These effects of inflammation are characterized by a decrease ...
We studiedexpression in both colorectal tumor cell lines and normal mucosa. Most of the lines lacked detectabletranscripts by Northern analysis. Large differences in expression were seen among normal mucosa of different patients with sporadic tumors. We analysed the coding region ofin eight colorectal ...