When chemotherapy is performed According to the colon cancer stage, therapeutic aims, patient’s age, and general health state, chemotherapy is given in the following modes. Neoadjuvant chemotherapyis administered prior to surgical intervention. It shrinks the tumor so that the specialist can remove i...
Chemotherapy, AdjuvantNeoplasm StagingClinical Trials as TopicColon cancer remains the third most common cancer, and cause of cancer-related death in the United States. Greater public awareness and acceptance of screening programs have contributed significantly to increasingly earlier detection of colon ...
Regimens used for adjuvant (postoperative) chemotherapy commonly include 5-FU with leucovorin or capecitabine, either alone or in combination with oxaliplatin.[2, 3, 4] Biologic agents employed to treat colon cancer include the following: Bevacizumab (Avastin) Cetuximab (Erbitux) Dabrafenib (Tafinlar...
Despite evidence of chemotherapy’s ability to cure or comfort those with colon cancer, nearly half of such Americans do not receive it. African Americans (AA) seem particularly disadvantaged. An ethnicity by poverty by health insurance interaction was hypothesized such that the multiplicative disadvant...
Despite evidence of chemotherapy’s ability to cure or comfort those with colon cancer, nearly half of such Americans do not receive it. African Americans (AA) seem particularly disadvantaged. An ethnicity by poverty by health insurance interaction was hypothesized such that the multiplicative disadvant...
component of colorectal cancer therapy, but patients often become resistant. Here, the authors identify a non-canonical function of glutamate-cysteine ligase modifier (GCLM) wherein its nuclear translocation increases NF-κB activity promoting resistance to platinum-based chemotherapy in colorectal cancer....
BACKGROUND: This article discusses peripheral neuropathy as a long-term side effect of oxaliplatin based chemotherapy, from a colon cancer survivor's perspective. Peripheral neuropathy is a common side effect of chemotherapy that affects quality of life for many cancer survivors. Severe and debilitating...
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths with an incidence rate of 40% in the United States and an average 5-year survival rate of < 15% in metastatic disease1. Chemotherapy of metastatic CRC has modest efficacy and is typically associated with toxic ...
Stage II– Partial colectomy is usually the first line of treatment for cancer that is at this stage. That being said, the doctor may also suggest adjuvant chemotherapy (chemo after surgery) if there’s a high risk of recurring (cancer coming back) ...
the necessity of a colostomy bag. In addition, delay means more aggressive treatment, including the possibility of radical surgery, radiation, and chemotherapy. Sometimes the delay is so great that premature death cannot be avoided. Types of harm caused by delayed damage of colorectal cancer ...