The findings are intriguing and supported from other perspectives. For example, Laron syndrome (LS) is a rare genetic condition, characterized with congenital deficiency of insulin-like growth factor-1 and dwar
Colon cancer is the third leading cause of cancer in the U.S. Learn about colon cancer symptoms, causes, treatment, survival rates, stages, and surgery.
Over the past few decades, the occurrence of the colonic diseases has been increased globally, and the demand for its effective treatment through safer drug therapies is quite high. Globally, colorectal cancer (CRC)1 is the third most commonly diagnosed cancer causing more than 2 lakh annual dea...
8.2.3.1.1Genomic instability: an evolving hallmark of colon cancer Most colon cancers are characterized by genomic instability. This is the result of genomic alterations during cell division. Damage to multiple genes that control cell division and tumor suppressors results in the development of cancer...
Colon cancer is the most common type of gastrointestinal cancer. It is a multifactorial disease process, with etiology encompassing genetic factors, environmental exposures (including diet), and inflammatory conditions of the digestive tract. Surgery currently is the definitive treatment modality.[1] The...
Colorectal cancer may run in families. Colon cancer risk to an individual is even higher if more than one immediate family member (parents, siblings or children) has had colorectal cancer, and/or the family member developed the cancer at a young age (less than 55). Under these circumstances...
About 70% of patients with colon cancer are >65 years of age and the disease is rare under the age of 45 (2 per 100 000/year). survival In Europe the relative survival for adults diagnosed with colon cancer during 1995–99 was 72% at 1 year and 54% at 5 years. Five-year ...
Early-onset colon cancer is diagnosed in less than 10% of patients under the age of 50, usually having a preference for the distal colon. Initial misdiagnosis of early-onset colorectal cancer occurs in up to 50% of cases. We present a young female who was initially thought to have a ...
Overweight/obesity is now established as a risk factor (second only to smoking) for colon cancer [12]. Two-thirds of Americans and an estimated 2.3 billion people worldwide are either overweight (body mass index [BMI] 25–29.9 kg/m2) or obese (≥30 kg/m2) [12]. According to a recent...
“It’s important to mention that still the risk for colorectal cancer is low in people under 55. We don’t want to be alarmists. The risk is low,” Siegel said. “In whites, the increase over the past decade was a 14% increase in the rate. So it’s not enormous, but it’s co...