Sprayable and thrombin suspensions such as CellSpray (Cambridge, the United Kingdom) and Bioseed-S (BioTissue, Freiberg, Germany) are not yet commercially available in the United States, with the exception of R
NCT01884376Implantation of Neuromaix during a diagnostic nerve biopsySural nervePNINAGermany[250] NCT01809002Implantation of bovine collagen-based nerve cuffPeripheral nervePNI3AmericaClinicaltrials.gov NCT04353908Subcutaneous collagen injection of porcine originFacial nervePNINAItaly[251] ...
et al. Functional tooth restoration by next-generation bio-hybrid implant as a bio-hybrid artificial organ replacement therapy. Sci Rep 4, 6044 (2014). CAS PubMed PubMed Central Google Scholar Wu, S., Liu, X., Yeung, K. W., Liu, C. & Yang, X. Biomimetic porous scaffolds for ...
The solubilized pro-MMP-1 was then concentrated and purified using ultrafiltration and Ni-NTA agarose resin (Qiagen, Hilden, Germany). Pro-MMP-1 was activated by TPCK-trypsin (Thermo Scientific), which cleaved the pro-MMP-1 propeptide. Active MMP-1 was purified by gel filtration on a ...
Intensity and FLIM data were collected by a H7422 GaAsP photon-counting photomultiplier tube (PMT; Hamamatsu, Bridgewater, NJ) connected to a time-correlated single photon counting (TCSPC) system (SPC-730, Becker & Hickl, Berlin, Germany). Multiphoton spectral lifetime imaging microscopy (SLIM) ...
6′-diamidino-2-phenylindole (H-1500 Vector Laboratories, Burlingame, CA) to identify nuclei. Images were acquired on a Leica microscope fitted with 20× objective using Leica Application Suite Advance Fluorescence software and the Thunder Imager from Leica (Leica Microsystems, Wetzlar, Germany). Sem...
However, in clinical situations with severe bone resorption of the alveolar process, which results in non-self-containing bone defects, the use of particulate bone replacement grafts with its inherent weak volumetric stability may limit the predictability of the regenerative therapy [5, 6]. In ...
Signal strengths were quantified using a densitometric program (TINA; Raytest Isotopenmeβgerate, Staubenhardt, Germany). No PCR products were obtained in control reactions without reverse transcriptase. After normalizing versus GAPDH intensity, percentage increase or decrease was determined. Each ...
Coli (GeneArt® Gene Synthesis, Germany). Subsequently, in order to further stabilize the triple helix and allow for subsequent functionalization via thiol–acrylate chemistry, an additional GGPCPPC sequence was added at the N terminal between the spacer sequence and the CL domain, using the ...
Furthermore, in published Federal Republic of Germany patent application No. 20 51 850, there are described pharmaceutical compositions which are characterized in that they contain an active material in combination with a polylactide or a copolymer of lactide and glycolide units. SUMMARY OF THE ...