Definition: Series of nucleotides that specify a specific amino acid during translation (a step in protein synthesis) Table of Contents What does codon mean?Acodon,inbiology, is the basic genetic unit of life that acts as the template for theamino acidsynthesis required forproteinexpression. All ...
Translation in Biology | Definition & Process DNA Translation Lesson for Kids: Definition & Sequence tRNA in Protein Synthesis | Structure & Role Protein Synthesis Overview, Function & Steps Protein Synthesis Lesson Plan Protein Synthesis Project Ideas Protein Synthesis Activities & Games Protein Formation...
ORFSCANNINGtakes codon usage into account to facilitate the location of genes, since realEXONSare likely to display a bias for certain codons, whereas runs of chance triplets will not. Codon usage is also called codon bias. Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. ...
(Science: molecular biology) The three codons, UAA known as ochre, UAG as amber and UGA as opal, that do not code for an amino acid but act as signals for the termination of protein synthesis. They are not represented by any tRNA and termination is catalysed by protein release factors. ...
David P.Clark,Nanette J.Pazdernik, inMolecular Biology (Second Edition), 2013 2.3Nonsense Mutations Cause Premature Polypeptide Chain Termination Not all codons encodeamino acids. Three (UAA, UAG, and UGA) arestop codonsthat signal the end of a polypeptide chain. Anonsense mutationoccurs when th...
Definition Chapters and Articles Related Terms Chapters and Articles You might find these chapters and articles relevant to this topic. RNA Editing RalfBundschuh, inMethods in Enzymology, 2007 5DETERMINING START AND STOP CODONS 5.1Summary Once the genomic region in which the gene is located has been...
Moreover, these codons were not only non- optimal, and thus by definition are rare in highly tran- scribed genes, but their exact matching tRNAs were ab- sent in the genome, and thus require wobble tRNAs, a combination that would in theory make them especially prone to slowing down ...
BMC Evolutionary Biology volume 9, Article number: 285 (2009) Cite this article 9484 Accesses Metrics details Abstract Background Codon usage may vary significantly between different organisms and between genes within the same organism. Several evolutionary processes have been postulated to be the ...
The central dogma of molecular biology suggests that synonymous muta- tions — those that do not alter the encoded amino acid — will have no effect on the resulting protein sequence and, therefore, no effect on cellular func- tion, organismal fitness or evolution. Nonetheless, in most ...
The absence of values might be a result of the extraordinarily short sequences which are unable to rightly encode enough amino acid, according to the definition of ENc and the calculation of CodonW [4]. Based on the 59 synonymous codons, a set of 37 genes were represented by the points ...