When the diagnosis is known, coding must be "to the highest degree of specificity," meaning the most precise code that fully explains the narrative symptom or diagnosis. ICD-9 codes have 3, 4, or 5 digits, so if
Golfos concurs: “Essentially, whether you’re coding for cataracts, hypertension, or any other diagnosis, if you’re not coding to the highest degree of specificity, it can easily affect reimbursement. If it’s an issue of medical necessity, you may use a less specific code when the payer...
The ICD-10-CM classifies deep vein thrombosis with a high degree of specificity based on severity, affected extremity, vein location, and laterality, but without detailed clinical documentation or consistent terminology use, coders may need to query providers often for clarification in order to assign...
MOCCI, a paralog of the NDUFA4 subunit of cytochrome C oxidase (Complex IV), replaces NDUFA4 in Complex IV during inflammation to lower mitochondrial membrane potential and reduce ROS production, leading to cyto-protection and dampened immune response. The MOCCI transcript also generates miR-...
ofthepatientforthatvisitor procedureassupplementary information.Donotcodea diagnosisthatisnolonger applicable. HCFAGuidelines Codetothehighestdegreeof specificity.Carrythenumerical codetothe4thor5thdigitwhen necessary.Remember,thereare onlyapproximately100validthree digitcodes;allotherICD-9codes requireadditionaldigi...
Arrayed CRISPR libraries extend the scope of gene-perturbation screens to non-selectable cell phenotypes. However, library generation requires assembling thousands of vectors expressing single-guide RNAs (sgRNAs). Here, by leveraging massively parallel plasmid-cloning methodology, we show that arrayed libr...
and specificity is ensured by no labelling of vagal motor neurons (Extended Data Fig.1e–w). VSNs that project to adjoining regions between two organs, such as the oesophageal and pyloric sphincters, can be accurately identified with UPBs from both organs as AAVrg slightly diffuses to adjac...
PTO is nuclease-resistant and highly soluble; however, its specificity and affinity are insufficient and sometimes incur off-target effects, such as non-specific protein downregulation and cell apoptosis47,48. The second-generation 2′-O-substituted ASOs have stronger binding ability49, greater ...
mRNA-like long non-coding RNAs (lncRNAs) are a significant component of mammalian transcriptomes, although most are expressed only at low levels, with high tissue-specificity and/or at specific developmental stages. Thus, in many cases lncRNA detection b
A long-standing goal in neuroscience is to understand how a circuit’s form influences its function. Here, we reconstruct and analyze a synaptic wiring diagram of the larval zebrafish brainstem to predict key functional properties and validate them throu