在基因组学研究中,编码序列(Coding Sequence, CDS)是解析基因功能的核心单元。它直接对应蛋白质的氨基酸序列,是DNA中真正参与编码生命活动的“有效信息段”。本文将系统解析CDS的定义、生物学意义及其在科研与实际应用中的价值。 CDS:从DNA到蛋白质的精准映射 CDS是DNA中能够被转录为成熟m...
Heat map displaying 836 coding sequences (CDS) that are not uniformly expressed in the four libraries and showing a standard deviation of 1 or more regarding the log(10) transformat...
The CDS is the region of the mRNA whose fate is to be translated, as its nucleotide sequence instructs the amino acid sequence of the protein, and that is why mRNAs are transcripts that primarily exert a coding function. However, there are cancer-relevant examples by which the CDS exerts a...
Further experiments in maize with transgenes individually expressing three crystal (Cry) proteins from Bacillus thuringiensis (Bt) tested the impact of CDS recoding using different codon bias tables. Transgenes with higher GC content exhibited increased transcript and protein accumulation. These results ...
(3′-UTR), coding sequences (CDS) and 5′-untranslated region (5′-UTR) [17,18]. When this biological function is considered in its deep complexity, it can be concluded that more than 60% of human mRNAs are regulated by miRNAs [17,18]. The miRNA/mRNA interaction causes translational ...
Previous investigation of coding sequence lengths (CDS) in the bacterial circular chromosome revealed short range correlation in the series of these data. We have further analyzed the averaged periodograms of these series and we found that the organization of CDS can be well described by first orde...
Gene Expression* Knockouts* Mass Spectrometry Mitochondria function or biology alternative translation short ORF According to the traditional view of protein synthesis, each protein-coding gene harbors a single annotated open reading frames (ORF)1 or coding sequence (CDS) encoding a canonical protein....
Only coding sequences (CDS) of protein-coding genes were considered, while lncRNAs were strictly filtered by distance to protein-coding genes, transcript biotype, gene length, evolutionary conservation and RNA expression. For benchmarking, we ran ExInAtor2 using the same PCAWG annotations. Evaluation...
coding sequence (CDS) a genome sequence bounded by a start and stop codon that encodes theAMINO ACIDSof a protein. Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005 Want to thank TFD for its existence?Tell a friend about us, add a link...
The nucleotide sequences of the present invention are also useful for producing large quantities of MPD, preferably human MPD, to be used as a starting material in the chemical synthesis of polyisoprene-containing compounds that include, but are not limited to, taxol. ...