3 Additionally, it has been found that glycolysis in cancer cells is regulated by N6-methyladenosine modifications in several mRNAs. Pyruvate dehydrogenase kinase 4 is involved in N6-methyladenosine-regulated glycolysis. When the 5′ untranslated region (UTR) of pyruvate dehydrogenase kinase 4 is ...
cmaniRa-l3so4 rdeigreucltaltye Snail expression [144,161,162], a regulatory mechanism that has indeed been described in both normal tissue homeostasis [161,162] and pathologic contexts such as ovarian cancer [162]. miR-34 directly targets Snail 3′ untranslated region (UTR), leading to ...
3. Results 3.1. Transgenic FLAG:AGO4 Functions Like Endogenous AGO4 In order to identify the population of RNAs associated with AGO4, a FLAG:AGO4 transgene, driven by the cauliflower mosaic virus 35S promoter, was transformed into ago4-1 (A. thaliana ecotype Landsberg erecta or Ler) mutant...