This study investigates the interaction between long non-coding RNAs (lncRNAs) and metabolic risk factors that contribute to coronary artery disease (CAD). A total transcriptome high throughput sequencing study was conducted on peripheral blood mononuclear cells from five patients with CAD and five ...
To evaluate the coding, recording and incidence of coronary heart disease (CHD) in primary care electronic medical records. Data were drawn from the UK General Practice Research Database. Analyses evaluated the occurrence of 271 READ medical diagnostic codes, including categories for 'Angina', 'Myoc...
Y CHROMOSOME-LINKED LONG NON-CODING RNA: FUNCTION AND INVOLVEMENT IN DIABETES WITH IMPLICATIONS FOR CORONARY ARTERY DISEASEAim of the study arm LIPIDOGRAM... E Molina,S Myers,G Chew,... - Scientific Meeting of the 被引量: 0发表: 2014年 Recombinant vaccinia virus incorporated with gene coding...
Increased expression or mutations in ANRIL are also associated with atherosclerosis, coronary artery disease, and stroke56,57,58,59. ANRIL expression correlated with chromosome 9p21.3 variants was thought to be a novel genetic marker for the risk of stroke and its recurrence60. In cerebral ...
(2019). A novel circRNA-miRNA-mRNA network identifies circ-YOD1 as a biomarker for coronary artery disease. Science and Reports, 9(1), 18314. https://doi.org/10.1038/s41598-019-54603-2 Article CAS Google Scholar Chang, T. Y., Tsai, W. C., Huang, T. S., Su, S. H., Chang...
The long non-coding RNA ANRIL is the best replicated genetic risk locus of coronary artery disease (CAD) and periodontitis (PD), and is independently assoc... Gregor,Bochenek,Robert,... - 《Human Molecular Genetics》 被引量: 137发表: 2013年 5'-noncoding region sacR is the target of all...
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat. Genet. 44, 890–894 (2012). Article CAS Google Scholar Willer, C.J., Li, Y. & Abecasis, G.R. METAL: fast and efficient meta-analysis of genomewide association scans. ...
Genetically regulated long non-coding RNAs (lncRNAs) in coronary artery disease (CAD) have not been investigated. To discover CAD-relevant lncRNAs, we performed the transcriptome-wide association study (TWAS) using a subset genomic data of CARDIoGRAMplusC4D Consortium and transcriptomic data of nine ...
Identifying candidate circulating RNA markers for coronary artery disease by deep RNA-sequencing in human plasma. Cells 11, 3191 (2022). CAS PubMed PubMed Central Google Scholar Mattick, J. S. RNA regulation: a new genetics. Nat. Rev. Genet. 5, 316–323 (2004). CAS PubMed Google ...
Coronary artery disease (CAD) and its most important complication, myocardial infarction (MI), results primarily from atherosclerosis, an inflammatory disease of the large arteries characterized by lipid-rich lesions. Genome-wide association studies (GWASs) have identified ∼200 risk loci for CAD/MI...