The variance of the evolutionary rate is not quite as large as data indicate under the model, and additional factors, such as environmental change or population-size fluctuation, need to be considered. Weak sel
PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions. Bioinformatics 27, i275–i282 (2011). Article PubMed PubMed Central CAS Google Scholar Dunham, I. et al. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57–74 (2012)...
HNRNPH1 was mutated in 26 cases (10%) when we consider both coding and noncoding mutations, placing it as the eighth most commonly mutated gene overall (Figure 1A; supplemental Figure 3). Despite limited coverage of introns by our sequencing assay, intronic variants were the most common type...
transfer RNAs (tRNAs), small nuclear RNAs (snRNAs), and small nucleolar RNAs (snoRNAs)) were the first ncRNAs to be identified and studied. They are up to ~4.5 kb long and ubiquitously expressed, as they are involved in essential processes...
除了转录体演化,其进行中的研究课题尚包含:蛋白质译码区(coding regions)演化机制、基因体大小决定因子、染色体上基 …enews.nhri.org.tw|基于2个网页 2. 区域 因为在DNA上,对应於某特定蛋白质的话密码区域(coding regions)彼此间可间隔一段相当长的距离,则在分裂型基因(split gene…tw.knowledge.yahoo.com|基于...
网络释义 1. 不转译区 ...列长度约为10kb,在5’端有著417 bps 的不转译区(non-coding regions),在不转译区后存在著两段无重叠 的转译区(open readi…www.docin.com|基于1 个网页 例句 释义: 全部,不转译区 更多例句筛选 1. The Feature Sequences of Coding and Non-coding Regions on Gene 基因中编...
[217]). Indeed, impaired RNA metabolism has been correlated with several neurodegenerative diseases. For example, abnormal repeat expansions in the non-coding regions of disease-related genes induce toxic gain-of-function of RNA in myotonic dystrophy, amyotrophic lateral sclerosis, and frontotemporal ...
网络非编码的 网络释义 1. 非编码的 最常用生物学专业英语词汇 - 豆丁网 ... nomenclature 命名法,术语noncoding非编码的noncyclic 非环式的 ... www.docin.com|基于3个网页 例句 释义: 全部,非编码的
4. Citing RNAcode === RNAcode: robust discrimination of coding and noncoding regions in comparative sequence data Washietl S, Findeiss S, Muller S, Kalkhof S, von Bergen M, Hofacker IL, Stadler PF, Goldman N RNA (2011), in revision 3. Contact === Stefan Washietl <wash@mit.edu>...
Elucidating functionality in non-coding regions is a key challenge in human genomics. It has been shown that intolerance to variation of coding and proximal non-coding sequence is a strong predictor of human disease relevance. Here, we integrate intolera