The resulting polypeptide products contain part of the canonical N terminus followed by a completely new intron-derived C-terminal sequence, 181 and 42 amino acids long for EGFR and AP1S1, respectively. It is unclear whether such observations are errors of splicing machinery or a functional ...
The stacked bar chart (right) shows the contribution of mutational processes to the hotspot mutations (Methods). Gene names are given when hotspots overlap functional elements (colour-coded), with amino acid (AA) alterations for protein-coding genes (solidus denotes substitution with any one of ...
Although the exact mechanism of packaging remains unclear, 7SL RNA was shown to be encapsidated into minimal VLPs containing a mini-Gag construct, which contains the first 12 amino acids of matrix followed by the C-terminal domain of CA and a leucine zipper in the place of NC (Keene et ...
Fig. 1 An integrative computational pipeline for the systematic identification and characteristics of lncRNAs inC. songorica.aInformatics pipeline for the identification of lncRNAs inC. songorica.bVenn chart showing the numbers of candidate lncRNAs filtered by the Pfam, CPC, CPAT and CNCI assemblies o...
The molecular-genetics of nitrogen assimilation into amino acids in higher plants. Annu Rev Plant Biol. 1996;47(1):569–93. Article CAS Google Scholar Shadchina TM, Dmitrieva VV. Leaf chlorophyll content as a possible diagnostic mean for the evaluation of plant nitrogen uptake from the soil....
The translation of lncRNAs can be modulated by many factors, including small or short open-reading frames (smORF or sORF) [19], eIF4E [20], and N6-methyladenosine (m6A) modification. lncRNAs lack canonical ORF codes for over 100 amino acids [19]. Therefore, they are considered untranslatable...
YTHDF3 binds m6A modified GAS5 and promotes its decay.aHeatmap showing the difference transcripts between normal and YTHDF3 knockdown groups.bMeta-gene analysis depicting different m6A peaks distribution between normal and YTHDF3 knockdown groups in a normalized transcripts.cPie chart show the diffe...
(thousand-and-one amino acids) protein kinases that involves in several different cellular processes including cell-signalling pathways32,41,42. TOAK2 has been suggested to be involved in the induction of apoptosis33. Here, we demonstrated that the predicted G4 sequence in the 5′ UTR ofTAOK2...
SLC7A5, also known as LAT1, encodes a large amino acid transporter located in the blood–brain barrier. It is essential in the maintenance of brain branched-chain amino acids' normal levels69. It was revealed that SCZ patients have an aberrant amino acid transport activities, such as the ...
FIG. 2 represents an amino acid sequence of a precursor of the γ-hANP, which sequence consists of 151 amino acids wherein a sequence of from 26 to 151 corresponds to the sequence of the γ-hANP set forth in FIG. 1; FIG. 3 represents a base sequence coding for the amino acid sequenc...