Cytochrome P-450c (Mr = 58 000 D) is the major cytochrome P-450 isozyme inducible by 尾-naphthoflavone (BNF) in cod ( Gadus morhua) liver. Polyclonal rabbit IgG against this form was used as an immunochemical probe to detect responses of cod larvae and juveniles to oil exposure. In ...
Groups of Atlantic cod and rainbow trout were treated (ip) with beta-naphthoflavone (BNF), phenobarbital, or peanut oil (controls), and properties of the hepatic xenobiotic and steroid metabolizing enzyme systems were evaluated. In both species, BNF treatment resulted in significant induction of ...