We also studied the influence of type of drug and comorbid disorders on psychostimulant efficacy. This is an update of the review previously published in 2010. For this updated review, we searched the Cochrane Drugs and Alcohol Group Trials Register, CENTRAL, MEDLINE, Embase and PsycINFO up to...
Cocaine is among the more lethal drugs of abuse. Its classic stimulant toxicity results from modulation of excitatory amino acids, central nervous system stimulation, and blockade of the reuptake of catecholamines. When combined, these properties produce the characteristic sympathomimetic toxic syndrome tha...
Cocaethylene, a metabolite of cocaine and ethanol, is a potent blocker of cardiac sodium channels. J Pharmacol Exp Ther. 1994;271(1):319–25. CAS PubMed Google Scholar United Nations Office on Drugs and Crime. World Drug Report 2014. United Nations publication, Sales No. E.14.XI.7. ...
Cocaine use disorder causes a host of medical, psychological, and social problems worldwide, including cardiovascular disease, infection, violence, and crime. The United Nations Office on Drugs and Crime [1] estimates that, in 2018, 19 million people used cocaine, a number that is expected to ...
Since it's an illegal drug, you can never be sure about the quality of cocaine. To make more money, dealers may “cut” the drug with other substances, like flour, baking soda, cornstarch, or talcum powder. They can also add other drugs like amphetamine, fentanyl, heroin, or procaine....
provide a functional assay that readily distinguishes the modes of action of amphetamine-like "DA-releasing" drugs from cocaine-like translocation blockers. ... MS Sonders,SJ Zhu,NR Zahniser,... - 《Journal of Neuroscience the Official Journal of the Society for Neuroscience》 被引量: 664发表...
Recent studies suggest the involvement of the N-methyl-D-aspartate (NMDA) type of glutamate receptors and nitric oxide synthase (NOS) in the process of inc... GC Palmer,B Clark,JB Hutchison - 《Drugs Future》 被引量: 76发表: 1993年 Preface [Hot Topic: Rational Drug Design and The Disco...
We offer this at Abbeycare, among other treatment options, to assist residents on the path to long-term recovery from alcohol and drugs. Learn More Individual Counselling Individual Counselling is a form of talk therapy that occurs in a private, confidential manner away from distractions. ...
Cocaine Detox Vs Other Drugs Relapse Rates What Factors Change Detoxing From Cocaine Pre-Existing Medical Conditions The following factors that change cocaine detox are either assessed ahead of admission, or a client is referred to an appropriate care facility for detox. Please speak to our admissio...
Treatment of cocaine-associated myocardial infarction has previously generally been conservative, using benzodiazepines, aspirin, glyceryl trinitrate, calcium channel blockers, and thrombolytic drugs. In the context of 10 patients with cocaine-associated myocardial infarction, who were treated with p...