Cocaine has pronounced peripheral vasoconstrictor effects. Despite the short half life of cocaine in the body these effects are relatively long-lived. The role of cocaine metabolites in vasoconstriction attributed to cocaine has not been reported. We evaluated the contractile ability of cocaine and ...
Crack Cocaine Side Effects on the Brain Since crack is smoked, the drug reaches a user’s brain incredibly quickly, stimulating the user’s reward system and rapidly increasing dopamine levels in their brain, which causes a potent rush of energy, confidence, and euphoria. This artificially high ...
Because crack is inhaled as a smoke, it reaches the brain much faster than inhaled powder cocaine. It can get to the brain and create a high within three to five minutes, compared to the 20 to 30 minutes it takes to feel the effects of snorted cocaine. On the downside, the crack coc...
>"But what about all the effects!" the unicorn exclaims. >"Well, it was probably a placebo effect," Twilight asks. >"What's a placebo?" Apple Bloom asks. >"A placebo is a substance or treatment with no active therapeutic effect. A placebo may be given to a person in order to...
Drug Effects on the Brain There has been an abundance of research released over the past 18 months shedding new light on an old problem --drug effects on the central nervous system. Three main themes arise. First, all drugs effect the brain - some very substantially, particularly in adolescen...
While cocaine was commonly used in medicinal tonics in the early 1900s, the United States outlawed the drug in 1914 after its harmful and addictive effects became better known. In the 1970s and 1980s, cocaine resurfaced as a popular drug on the club and party circuit. While cocaine use pe...
Cocaine Effects The drug sends high levels of dopamine, a natural chemical messenger in your body, into the parts of yourbrainthat control pleasure. This buildup causes intense feelings of energy and alertness called a high. You may feel: ...
Cocaine is astimulant drugthat can have many harmful effects on the body, including the eyes. These harmful effects include: 1. Ischemic optic neuropathy When cocaine is used repeatedly, it can cause blood vessels in the eyes to constrict, reducing blood flow to the eyes and leading to a co...
the Peruvian Indians as early as the sixth century to allay the effects ofcold, hunger, andfatigue. It is still used as such as a gift from the Sun God. In this sense, coca is an important sociocultural tradition for Peruvian and Bolivian Indians and should not be confused with the ...
In the present study we examined the effects of cocaine seizure kindling on the expression of NMDA receptors and levels of extracellular glutamate in mouse brain. Quantitative autoradiography did not reveal any changes in binding of [<sup>3</sup>H] MK-801 to NMDA receptors in several brain reg...