"Because of its specific mechanism of action, we believe ONC-392 has the potential to broaden the reach of CTLA-4-targeting immunotherapy," said Yang Liu, PhD, Co-Founder, CEO and Chief Scientific Officer of OncoC4. "We very much look forward to working hand-in-hand with BioNTech in de...
Pestka, S.: Micrococcin and micrococcin P. In: Mechanism of action of antimicrobial and antitumor agents, (ed. J.W. Corcoran and F.E. Hahn), vol. III, p. 480–486. New York: Antibiotics 1975Pestka, S.: Micrococcin and micrococcin P. In: Mechanism of action of antimicrobial ...
the movement of cilia in infusorians, the disjunction of chromosomes during mitosis, and the injection of phage DNA into bacteria, appear to be based on the same molecular mechanism. This common mechanism involves a change in the conformation or the relative position of the fibrillar structures in...
aSolid-state reactive sintering mechanism for proton conducting ceramics 固体易反应的焊接机制为氢核举办的陶瓷[translate] aIn case of N-data points expressed as power of 4^v, we can employ radix-4 algorithm instead of radix-2 algorithm for more efficient estimation. If we consider a column-wise...
Hamm, R., Zeino, M., Frewert, S., and Efferth, T. (2014). Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B. Toxicol. Appl. Pharmacol. 281, 78–86.
BioNTech and OncoC4 will co-develop ONC-392 as monotherapy or in combination with anti-PD1 in various solid tumor indications, with a randomized Phase 3 trial planned to start in 2023.
10.3 The Entity shall establish a complaints or grievance mechanism appropriate to the nature, scale and impact of the business, to allow interested parties to voice concerns about circumstances in its supply chain involving Eligible and/or CoC Materials from Conflict-Affected Areas. 10.4 If the ...
The mechanism of virucidal action these polyphenolic compounds consisted in their direct binding to the H1N1 virus, thus preventing the penetration of the virus into cells and their infection in vitro (Roschek, Fink, McMichael, Li, & Alberte, 2009). Liu, Wang, Lee, Wang, and Du (2008) ...
Kim MH, Choi SH, Kim BH (2017) Skin wound healing effects and action mechanism of acai berry water extracts. Toxicol Res 33:149–156 Article CAS Google Scholar Kim HG, Jung YS, Oh SM, Oh HJ, Ko JH, Kim DO, Kang SC, Lee YG, Lee DY, Baek NI (2020) Coreolanceolins A-E, Ne...
Microorganisms of different species interact in several ecological niches, even causing infection. During the infectious process, a biofilm of single or multispecies can develop. Aspergillus fumigatus and Staphyloccocus aureus are etiologic agents that c