The Claisen condensation –strictly the condensation of two esters with the concomitant release of one of the constituent alcohol moieties – is arguably the most important carbon–carbon bond-forming reaction in biology, as it is used in the biosynthesis of fatty acids, polyketides, and a large...
The results of these tests are presented as whether the data indicated effects of strain of rat, meaning a statistical tendency for Sprague-Dawley rats to be different from Fischer-344 rats, independent of FiO2; similarly, a nota- tion of an effect of oxygen indicates a variable affected by ...
1996), meaning that northern blotting using probes specific for each isoform would clarify the issue. Specific inhibitors of HMG-CoA reductase, collectively known as statins, have proved very effective in the treatment of hypercholesterolaemia by lowering plasma total cholesterol and LDL levels, with...
1) that can be found in some eubacteria as well as all three eukaryotic kingdoms (plants, fungi and animals), meaning that it is more ancestral than leptin and ghrelin20,21. ACBP has the peculiarity to be secreted as a leaderless protein through a non-conventional (Golgi-dependent) ...
It should be underlined that, under anaerobic conditions, both Pox and Acs activities were high (Table 4), meaning that i) Pta-Ack is not the sole acetate-producing pathway in E. coli and ii) the co-expression of Pox and Acs pathways could lead to an acetate-consuming cycle with lower...
jointly reducing IPD to around 93 cm. Meaning that not only masks additionally vaccination may lead to the shortening of IPD and may trigger challenges in the avoidance and control of COVID-19 transmission.Exposure to family violence (EFV) is suggested as a relevant antecedent of child-to-paren...
It should also be noted that both HaloMS as well as HaloMCL can act as malyl-CoA thioesterases, meaning that they are able to use malyl-CoA as substrate, in contrast to the canonical malate synthases [35, 38]. Moreover, both haloarchaeal enzymes also release malyl-CoA as the product ...
Unless defined otherwise herein, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. As used herein, the singular terms “a,”“an,” and “the” include the plural reference unless ...
Acetyl-CoA synthetase or Acetate-CoA ligase is an enzyme involved in metabolism of carbon sugars. It is in the ligase class of enzymes, meaning that it catalyzes the formation of a new chemical bond between two large molecules. The two molecules joined specifically by acetyl-CoA synthetase are...
The term “nucleic acid construct” is understood as meaning artificial structures which are composed of nucleic acid and which can be transcribed in the target cells. They are preferably inserted into a vector, for example into non-viral vectors, such as plasmids, or viral vectors. The skilled...