Co-translational processing and intracellular transport of rat salivary mucus glycoproteinA preparation of peptidyl-tRNA from intact microsomes of mucin-synthesizing polysomes of sublingual salivary gland cells contained fatty-acylated galactosamine-free and galactosamine-enriched peptidyl-tRNA fractions, whereas...
Importins (also called karyopherins) are nuclear transport receptors (NTRs) that bind the nuclear localization sequences (NLSs) of their cargo in the cytoplasm and facilitate its passage through nuclear pore complexes (NPCs) into the nucleoplasm5. Moreover, importins contribute to proteostasis6. I...
The general AMBER force field (GAFF) can accurately predict thermodynamic and transport properties of many ionic liquids. J. Phys. Chem. B 119, 5882–5895 (2015). Article CAS PubMed Google Scholar Hollingsworth, S. A. & Dror, R. O. Molecular dynamics simulation for all. Neuron 99, ...
First, we investigated the co-translational landscape of Nic96 which contains several motifs to connect the inner ring to the nuclear envelope and the central transport Nup (CTN) trimer (Fig. 1c)15,16,36. Our RIP-qPCR data indicate a co-translational interaction of all three components of ...
ABC transporters transport a wealth of molecules across membranes and consist of transmembrane and cytosolic domains. Their activity cycle involves a tightly regulated and concerted domain choreography. Regulation is driven by the cytosolic domains and function by the transmembrane domains. Folding of these...
Etudes au microscope électronique du transport des protéines durant la traduction chez E. Coli, et de la terminaison de la traduction chez l'... Comparison of our RNCEspP-SRP-FtsY cryo-EM structure to other available cryo-EM structures of co-translational targeting complexes containing the ...
The general AMBER force field (GAFF) can accurately predict thermodynamic and transport properties of many ionic liquids. J. Phys. Chem. B 119, 5882–5895 (2015). Article CAS PubMed Google Scholar Hollingsworth, S. A. & Dror, R. O. Molecular dynamics simulation for all. Neuron 99, ...
the adsorption kinetics are governed by the diffusion of species to the substrate surface. In contrast, the spray LbL process employs convective transport, where deposition solutions are aerosolized and followed by spraying onto the substrate, significantly accelerating the assembly. This method reduces ...
It is suggested that the presence of structures that are incompatible with intercompartmental transport of vacuolar protein leads to retention of the mutated CpY by the endoplasmic reticulum.doi:10.1111/j.1574-6968.1993.tb06380.xMassoud Ramezani Rad...
This also imposes, due to the physical separation of the nuclear and cytoplasmic compartments, a special burden on the nucleocytoplasmic transport machinery5,6. Given the high abundance and difficult physicochemical properties of ribosomal proteins1,5,7, their correct folding and fail-safe targeting ...