Despite extensive research, the regulatory mechanisms underlying the pathogenesis and progression of ccRCC remain largely unknown.MethodsWe downloaded 5 ccRCC expression profiles from the Gene Expression Omnibus (GEO) database and obtained the list of differentially expressed genes (DEGs). Using String ...
Despite extensive research, the regulatory mechanisms underlying the pathogenesis and progression of ccRCC remain largely unknown.MethodsWe downloaded 5 ccRCC expression profiles from the Gene Expression Omnibus (GEO) database and obtained the list of differentially expressed genes (DEGs). Using String ...
The enrichment of functions associated with genes towards the top and bottom of this ranked gene list were assessed using the "GseaPreranked" tool within GSEA. Significance was determined by the stringent family-wise error (FWER) multiple testing correction p-value of less than or equal to 0.05...
Table S1. List of RNA-Seq samples. (DOCX 84 kb) Additional file 2: Table S2. The 303 epithelium scale-to-feather transition (SFT) genes. Column A and B are Ensembl gene ID and gene symbol, respectively. From column C to column F are normalized gene expression levels (CPM) for sample...
Cell type composition in each spatial transcriptome spots were computed using RCTD v.2.0.130 based on the spot mRNA expression and the marker gene list. For the intestine and SVZ datasets, we directly used cell type annotations from the original study7. Verification in scRNA-seq Dimension ...
Similarly, cluster enrichment and gene list enrichment analysis were performed, suggesting several genes are involved in different biological pathways or processes. Conclusions This study will help better understand the gene expression landscape in long COVID. However, it might help the discovery and ...
Enrichment analysis of gene and drug clusters To compute the functional enrichments of the common neighbor genes, either for the whole list of genes, or for the 49 common neighbor genes that were predicted to be targeted by FDA-approved drugs, we used the gprofiler Python package v.1.0.0 ...
Genomic evidence indicates that exoU acquisition is likely mediated by horizontal gene transfer (HGT) of the pathogenicity island PAPI-2, while deletion of exoU was sufficient to mitigate virulence in the exoS+/exoU+ strains. Furthermore, bioinformatics analysis showed that such exoS+/exoU+ P....
Physical proximity only accounts for a small proportion of this conservation, demonstrating that purely neutralist models of gene order evolution are not realistic.doi:10.1016/S0168-9525(02)02813-5Laurence D HurstElizabeth J.B WilliamsCsaba Pál...
Comparison of gene recommender with gene expression topomap; Expression profiles of genes in the retinoblastoma hit list; Coregulation of the retinoblastoma query list in DNA microarray experiments.OwenDepartmentArtDepartmentB.DepartmentStuartDepartment...