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the quinone structure in the molecule makes ubiquinone have two forms: oxidized (ubiquinone, Coenzyme Q10) and reduced (Ubiquinol, Ubiquinol), these two forms can be converted into each other in cells, which is the basis of ubiquinone as an electron transport body. The gain and loss of electr...
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Several analogues have so far been synthesized such as mito-Q and idebenone. Table 1 Effect of Co-Q10 supplementation on lipid metabolism in metabolic syndrome Full size table Mito-Q10 comprises a lipophilic triphenylphosphonium cation covalently attached to an ubiquinol antioxidant [136]. The ...
Moreover, the ALA/DHLA system is able to reduce ubiquinone (CoQ10) to ubiquinol, an important constituent of the mitochondrial electron transport chain, and to enhance the NAD(P)H/NAD(P)+ ratio, a component of cell redox state (Figure 1) [73,108]. Glutathione, which is implicated in...
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