Here, we describe the case of a COVID-19 patient who developed recurring ventilator-associated pneumonia caused by Pseudomonas aeruginosa that acquired increasing levels of antimicrobial resistance (AMR) in response to treatment. Metagenomic analysis revealed the AMR genotype, while immunol...
which can deteriorate into acute respiratory distress syndrome. The primary etiology may be attributed to cytokine storm, which is triggered by the excessive release of proinflammatory cytokines
Brandal LT, Ofitserova TS, Meijerink H, Rykkvin R, Lund HM, Hungnes O, Greve-Isdahl M, Bragsta K, Nygård K, Winje BA (2021) Minimal transmission of SARS-CoV‑2 from paediatric COVID-19 cases in primary schools, Norway, August to November 2020. Euro Surveill 26(1):2002011. ...
Abbreviations: ARDS: acute respiratory distress syndrome; GC: glucocorticoid; IC: intensive care; IV: intravenous; MV: mechanical ventilation. This review intends to summarize some of the effects of GCs on the major cellular and molecular components of the inflammatory/immune system, their use in ...
(COVID-19) can be divided into five groups, based on disease severity: asymptomatic, mild, moderate, severe, and critical (Gao et al.2021). Severe disease complications observed in a subset of COVID-19 patients include pneumonia, acute respiratory distress syndrome (ARDS) and cardiac injury ...
pathways during replication. Resistance may be less likely to develop against these agents because a single point mutation in the viral genome is unlikely to enable the virus to replicate independently of the targeted host factor. Another challenge in making antiviral agents against acute viral ...
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting thousands of people around the world. Urgent guidance for clinicians caring for the sickest of these patients is needed. Methods We...
a multi methods cross-sectional study. Three themes were identified, including (1) perceived participation restrictions for people with SCI and their loved ones, which revealed interruptions and changes in service provision during COVID-19, barriers and inconveniences to maintaining life habits and ...