588 Background Establishing the pathologic basis of focal brain lesions caused by disease processes such as CNS lymphoma is often difficult. Results of standard MRI-based neuro-imaging are non-specific and cytological testing of cerebrospinal fluid (CSF) is highly insensitive. We tested the ...
Learnthedifferentialdiagnosisofbrainmasses Understandthecommonimagingfeaturesofprimary CNSlymphomaonbothCTandMRI Learnthedifferencesinimagingfeaturesofprimary CNSlymphomabetweenimmunocompetentand immunocompromisedpatients UnderstandtheroleofimaginginprimaryCNS lymphoma ...
MRI of the brain showed multiple focal lesions with surrounding oedema. There was cerebrospinal fluid pleocytosis, and (EBV) DNA was detected in the spinal fluid by . A brain biopsy confirmed the suspicion of primary . EBV-associated primary is a relevant differential diagnosis in patients with ...
Development and validation of a machine learning algorithm for predicting diffuse midline glioma, H3 K27–altered, H3 K27 wild-type high-grade glioma, and primary CNS lymphoma of the brain midline in adults. J Neurosurg. 2023;139(2):393–401. Article CAS PubMed Google Scholar Yang N, ...
Here, the authors develop a deep learning method to diagnose primary nervous system lymphoma from stained whole-slide images. Xinke Zhang , Zihan Zhao & Muyan Cai Article 02 May 2024 | Open Access Response of treatment-naive brain metastases to stereotactic radiosurgery Current guidelines ...
Lymph node biopsy revealed systemic B-cell follicular lymphoma, grade 3A (negative for t(14;18), expressing CD19, CD20, HLA-DR, CD45 and sIg lambda). MRI brain showed patchy bilateral T2-weighted hyperintensities in a watershed distribution with scattered multifocal diffusion restriction and mild...
Primary CNS lymphoma (PCNSL) harbors mutations that reinforce B cell receptor (BCR) signaling. Ibrutinib, a Bruton's tyrosine kinase (BTK) inhibitor, targets BCR signaling and is particularly active in lymphomas with mutations altering the BCR subunit CD79B and MYD88. We performed a proof-of-...
Stein M, Kuten A, Ben-Arieh Y, Cohen Y, Haim N: Primary brain lymphoma. Harefuah 121:4–8, 1991. PubMed CAS Google Scholar Aerospace Medical Association: HIV Positivity and Aviation safety. Aviat Space Environ Med 63:375–77, 1992. Google Scholar Volberding PA, Lagakos SW, Kock MA...
In spite of several characteristic imaging finding on conventional MRI, it is difficult that the correct diagnosis of CNS lymphoma is difficult in the intracranial mass lesions. However, the correct diagnosis of CNS lymphoma is important, because the prognosis and treatment of CNS lymphoma are differ...
After early measurements in vitro in yeast cells [237], [U-2H, U-13C]-glucose was successfully used to measure glycolysis in murine lymphoma and lung tumors [211]. Low but measurable levels of the glycolytic intermediates DHAP and 6PG were observed, along with HCO3–, which was used to...