Hence, therapeutic efforts directed towards maintaining CSF circulation and CNS fluid homeostasis across the given life span may be beneficial for preserving cognitive health. Non-invasive magnetic resonance imaging (MRI) studies have shown that CSF moves from its major site of production—the choroid ...
ArticlePubMedCASGoogle Scholar Novick D, Haro JM, Suarez D, Marques-Teixeira J, Naber D. Clinical consequences of switching antipsychotic drugs in outpatients with schizophrenia: 36-month results from the European Schizophrenia Outpatient Health Outcomes study. Int Clin Psychopharmacol. 2008;23(4):203...
Marco Prinz 2,4,5 and Seija Lehnardt 1,6,* 1 Institute of Cell Biology and Neurobiology, Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany; thomas.wallach@charite.de (T....
The efficacy of modafinil 200 or 400 mg/day was rated as good or excellent (using a 4-point scale) in 84 of 131 evaluable patients (64%) with excessive daytime sleepiness treated for 1 to 114 months in a noncomparative study. 53 patients withdrew from the study (43 because of loss of...
Thus, modafinil is effective in the treatment of EDS in patients with narcolepsy, although it is not effective against cataplexy. Preliminary findings indicate that, unlike other psychostimulants, the drug is unlikely to be abused and is not associated with withdrawal phenomena. Therefore, modafinil...