Methods Using hospital ICD-10 codes for acquired demyelinating syndromes from a nationwide register and subsequent chart review, we identified 52 children (<18 years) with ADEM and 66 children with MS. We undertook a retrospective analysis of MRI scans at onset and at follow-up. The MRI rater...
If the balance tips towards one side, it can cause neoplastic proliferation, while on the other spectrum can lead to extensive demyelination. Female MS patients were more likely to have both neurological conditions. The average age was 62.2 years, speculating that some of these patients still had...
Our data show that co-administration of E2 and IL-10+ B cells ameliorates EAE disease severity and limits CNS infiltrating leukocytes in B cell deficient mice. Additionally, treatment with E2 and Bregs reduces demyelination and dramatically decreases the proportion of CD11b+CD45hi activated ...