Current recommendations for prevention of virus transmission are based on data published 20 y ago in the context of human milk banking. Two recent clinical trials examined storage of breast milk at -20 degrees Celsius to reduce virus transmission. However, in both studies, CMV transmission occurred...
whereas cell-free supernatants from co-culture experiments also inhibited virus spread, implying that soluble factors were critically needed. Interestingly, the antiviral effect was independent of IFN-γ, TNF-α, and IFN-I as indicated by cytokine inhibition experiments using neutralizing antibodies or ...
Careful hygiene can help prevent transmission of the virus. But, since CMV is very common, is present in most body fluids, and is passed through close contact, most people are infected early in life. It has been estimated that as many as 70% of children in daycare have been exposed to ...
Cytomegalovirus (pronounced si-to-MEG-a-lo-virus), or CMV, is a virus that belongs to theHerpesviridaefamily, hence its older name, "human herpesvirus 5 (HHV 5)". Other members of this family include herpessimplex viruses(which causecold soresand genital herpes),varicella-zoster virus(which ...
30.itell,h.l.,c.s.nelson,d.r.martinez,ands.r.permar.2017.maternalimmunecorrelatesofprotectionagainstplacentaltransmissionofcytomegalovirus.placenta60suppl1:s73–s79. 31.jackson,s.e.,g.m.mason,andm.r.wills.2011.humancytomegalovirusimmunityandimmuneevasion.virusresearch157:151–160. ...
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Ignored virus in pregnant mothers has serious effects The purpose was to evaluate the effect of accuracy of therapy with Ganciclovir and Valganciclovir (correct indication, drug dosage, duration of treatment, etc.) on the patient's outcome mainly considering the failure of antiviral therapy, recurrenc...
DOI: 10.1203/01.PDR.0000139483.35087.BE mission from breast milk to preterm infants is clinically important, then prevention of virus transmission will be critical (4). Recent recommendations for virus inactivation in human milk by freezing, which destroys the virus (5,6), are still based on ...
Gupta G, Yakubu I, Bhati CS, et al. Ultra-short duration direct acting antiviral prophylaxis to prevent virus transmission from hepatitis C viremic donors to hepatitis C negative kidney transplant recipients.Am J Transplant. 2020;20(3):739–751. ...
16.StagnoS,WhitleyRJ.Herpesvirusinfec-tionsofpregnancy.I.CytomegalovirusandEpstein-Barrvirusinfections.NEnglJMed1985;313:1270-4. 17.StagnoS,PassRF,CloudG,etal.Primarycytomegalovirusinfectioninpregnancy:inci-dence,transmissiontofetus,andclinicalout-come.JAMA1986;256:1904-8. 18.Cui,X.;Churchill,G.A.(20...