In the present study, we found that the genomic sequence of the HCMV-DB strain isolated from a cervical swab specimen is close to the sequence of other primary clinical isolates, especially the Toledo strain, originally isolated in the urine of a child presenting a congenital infection by HCMV...
Primary urine derived HCMV (uCMV) infects fibroblasts much more efficiently than epithelial cells, although even a single passage in fibroblasts is sufficient to improve efficiency of epithelial cell entry [102]. These results may indicate that fibroblasts act as a launching platform for virus able...