In contrast, MilA accepts the ribose form more efficiently than the deoxyribose form, which makes it unique. The substrate CMP is bound in a deep active-site pocket of MilA, in a manner similar to the binding of dUMP by T4 CH and TS (Fig. 3). Most of the key amino acids involved...
The resulting analysis con- firmed the loss of full length CMAH protein in the fibroblast cells Table 1 | Efficiency of CMAH targeting in fibroblast cells using ZFN and donor DNA. Female cells showed decrease efficiency of the targeting event Source of cells Source of ZFN No. of cells ...
Show full outline Cited by (147) Figures (13) Show 7 more figures Tables (1) Table Extras (4) Download all Document S1. Tables S3 and S5 Table S1. Pycsar systems identified in this study, related to Figure 2 Table S2. Mutant phages isolated in this study, related to Figure 6 ...