Whether it is an early phase gene therapy or commercial scale protein therapeutic, we partner with customers at every stage of their manufacturing journey to provide appropriate risk management solutions and protect the customers’ patients we ultimately serve. 2024-10-23 Video Navigating ...
As mentioned above, the GRA process starts with the assessment of the API synthetic route for postulated and/or known impurities using structural alerts as the key determinant, i.e. identification of PGIs. At this stage there are two key unknowns: Is the PGI actual...
Badparvar F, Marjani AP, Salehi R, Ramezani F (2024) Dual pH/redox-responsive hyperbranched polymeric nanocarriers with TME-trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer. Sci Rep 14:8567. https://doi.org/10.1038/s41598-024-57296-4 Article CAS ...
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Unlike an inactivated vaccine, which uses a whole dead targeted virus, and a vector vaccine, which uses a chemically weakened second virus as a carrier, a recombinant protein vaccine uses only part of the targeted virus to trigger a protective immune response. ...