The use of cluster randomized trials (CRTs) is increasing, along with the variety in their design and analysis. The simplest approach for their sample size... C Rutterford,A Copas,S Eldridge - 《International Journal of Epidemiology》 被引量: 44发表: 2015年 Methods for sample size determinati...
In this paper we discuss the application of cluster-randomized intervention studies to simulation-based evaluation of surgical care policies, arguing that the methodological rigour of evaluative studies should be applied to the design and analysis of simulation experiments. We introduce a framework and ...
Methods/Design This prospective, geographically clustered randomized field experiment is enrolling participants into two arms: a control arm that receives standard HIV testing and referral for treatment; and an intervention arm that receives an evidence-based, woman-focused behavioral intervention that empha...
Cluster-Randomized and Quasi-Experimental Studies: Design and Analysis RTI works closely with clients and collaborators to ensure the most practical and robust designs possible, both to minimize potential bias and to maximize generalizability. During data analysis, we use methodologies that account for ...
The second phase is an impact evaluation, in which we will use a Hybrid Trial Type 2 Effectiveness-Implementation study design to determine the overall effectiveness of this digital intervention as well as the relative effectiveness of the two different school-based implementation models. This takes ...
Statistical methods Randomization To optimize compliance and generalizability, a cluster- randomized design will be utilized. All participants working in the same clinical unit will be assigned to wear the same respiratory protective equipment (i.e., an N95 or MM) during patient interactions for the...
三臂式集群随机控制试验的设计
DesignandAnalysisofClusterRandomizedTrialsCatherineM.CrespiMay2019Contents1ClusterRandomizedTrials11.1Introduction...21.2Randomization...31.2.1Matchingandstratification...31.2.2Constrainedrandomization...41.2.3Minimization...41.3Analysis...51.3.1Continuousoutcomes...51.3.1.1Model...61.3.1.2Estimationandinferen...
Cluster-randomized trials represent an important experimental design, supplementing ordinary randomized clinical trials. They are particularly relevant when evaluating interventions at the level of clinic, hospital, district or region. They are necessary when it is not feasible to randomize individual patient...
The stepped-wedge cluster randomized design has been increasingly employed by pragmatic trials in health services research. In this study, based on the GEE approach, we present closed-form sample size calculation that is applicable to both closed-cohort and cross-sectional stepped wedge trials. Impor...