The article discusses the use of cluster randomised trials (CRT) for interventions delivered at a group level. Topics mentioned include the clusters of individuals that are randomised to the intervention or control in a CRT, the aspects to consider in a CRT, such as the clustering of ...
Cluster Randomised Trials, Second Editionthoroughly describes the aspects of CRT designs and the analysis of data from such trials. After presenting some basic concepts, Hayes and Moulton focus on the clustering aspect of the design. They cover between- and within-cluster variability and correlation,...
A cluster randomised trial (CRT) isa randomised controlled trial in which pre-existing groups, called clusters, of individuals are randomly allocated to treatment arms. For example, clusters may be clinical practices or schools where the individuals are patients and school children, respectively. Sandr...
Campbell MK, Grimshaw JM: Cluster randomised trials: time for improvement. The implications of adopting a cluster design are still largely being ignored. BMJ. 1998, 317 (7167): 1171-1172. Article CAS PubMed PubMed Central Google Scholar COMMIT Research Group: Community Intervention trial for ...
Kate MackayWhittington Hospital NHS TrustLondonJohn MoreirasWhittington Hospital NHS TrustLondonThe Clinical TeacherMorrissey B, Jacob H, Harnik E, et al. Simulation in un- dergraduate paediatrics: a cluster-randomized trial. Clin Teach 2016;13(5):337-42....
How cluster trials are often used to prevent such contamination between intervention and control groups; Comparison of size between cluster trials and individually randomized trials; Suggestion that problems of contamination can often be overcome by increasing the sample size.Diana Elbourne...
Eldridge S, Kerry S, Torgerson DJ: Bias in identifying and recruiting participants in cluster randomised trials: what can be done? BMJ 2010, 340:36-39.Eldridge, S, Kerry, S, Torgerson, D (2010) Bias in identifying and recruiting participants in cluster randomised trials: what can be done...
A hybrid type 2 effectiveness implementation cluster randomised controlled trial will be implemented in the state of Goa, India. Twenty-eight clusters of villages and their associated public sector health centres will be randomly allocated through restricted randomisation. Clusters will be randomly allocate...
The stepped wedge cluster randomised trial: Rationale, design, analysis, and reporting The stepped wedge cluster randomised trial is a novel research study design that is increasingly being used in the evaluation of service delivery type interventions. The design involves random and sequential crossover...
Effectiveness of a childhood obesity prevention programme delivered through schools, targeting 6 and 7 years olds: Cluster randomised controlled trial (waves study). BMJ 2018, 360, k211. [CrossRef] [PubMed]Adab P, Pallan MJ, Lancashire ER, et al. (2018) Effectiveness of a childhood obesity...